S2-DRSC

DGRC Stock Number: 181

RRID: RRID:CVCL_Z992

Synonyms: S2 , SL2 , Schneider's 2 , Schneider's line 2

Donor: N. Perrimon and B. Mathey-Prevot

FlyBase Report: FBtc0000181

Cellosaurus Report: CVCL_Z992

Features:

  • isolate of S2 used for RNAi in the DRSC
  • modENCODE line
  • authenticated

Categories:

  • Dm Embryonic

S2 Isolate Backround

At the beginning of the modENCODE project, it was desirable to designate a single S2 isolate to be used throughout the project and by members of the community who wished to take advantage of modENCODE-produced data; the desired attributes of this isolate were that it be easy to culture and known to be sensitive to RNAi treatment. For this purpose, Norbert Perrimon donated to the DGRC the isolate of S2 cells that were used for RNAi-based screens at the DRSC; we named this isolate S2-DRSC. Perrimon had received S2 cells from several labs (including the Cherbas lab), and the relationship between S2-DRSC and S2-DGRC is unknown. Note: This line is named for the DRSC (Drosophila RNAi Screening Center).




Price: $357.00

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To cite S2-DRSC

When publishing experiments using S2-DRSC, please include the following details in your manuscript.

  • Materials and Methods
    S2-DRSC (DGRC Stock 181 ; https://dgrc.bio.indiana.edu//stock/181 ; RRID:CVCL_Z992)
  • Acknowledgements
    • Drosophila Genomics Resource Center (NIH Grant 2P40OD010949)
  • References
    Schneider, 1972, J. Embryol. exp. Morphol. 27: 353--365 FBrf0024118 PMID:4625067
modENCODE data Sex | Copy Number Variation | sRNA
Recommended Medium
  • M3+BPYE + 10% FCS
  • Schneider's + 10% FCS
Species D melanogaster
Parent Line isolate of Schneider's line 2
Primary Reference FBrf0024118
Lab Of Origin Schneider
Stage Source late embryonic stage
Tissue Source embryo
Sex male ( basis: expression levels of roX genes, msl-2 and traF; splicing patterns of tra and Sxl )
Source Strain: Oregon R
Doubling Time
  • M3+BPYE + 10% FCS: 46 hrs
  • Schneider's + 10% FCS: 93 hrs

All times are approximate (hrs, 25° unless otherwise noted).