About the DGRC

The Drosophila Genomics Resource Center (DGRC) serves the Drosophila research community by: (a) collecting and distributing DNA clones and vectors; (b) collecting and distributing Drosophila cell lines; (c) developing and testing genomics technologies for use in Drosophila and assisting members of the research community in their use.

All orders must be initiated through this website.

cDNAs and Vectors

The DGRC has assembled a large (over 1,000,000 and expanding) inventory of DNA clones through the generosity of individual community members, the BDGP, and the CuraGen Corporation. The collection includes transformation vectors, cDNA clones, and the CuraGen yeast two-hybrid collection. Clone collections and common vectors are listed in the catalog.

All orders must be initiated through this website.

Cell Lines

The DGRC has sought to collect as many cell lines as possible representing D. melanogaster and closely related species. The collection currently includes 163 lines and will continue to grow.

Cell lines, with brief descriptions, are listed in the catalog.

All orders must be initiated through this website.

Shipping Hotspots

Browse a larger map of US zip codes and foreign cities that the DGRC has shipped to.

All orders must be initiated through this website.

The DGRC was created by the Center for Genomics and Bioinformatics (CGB), Indiana University, Bloomington, and is supported by a grant from the National Institutes of Health (ORIP and NIGMS). The DGRC is directed by Peter Cherbas and its work is guided by an advisory board representing the Drosophila research community.


Tools for phiC31 integrase-mediated replacement in Drosophila cell lines

The DGRC is pleased to offer a series of cell lines carrying single phiC31 docking sites for targeted replacement, along with a series of plasmids designed for use with these lines. The materials are described in a pair of papers to be published in the December 1, 2015 issue of Genetics, one from Amanda Simcox's lab and one from the DGRC. The 2 lines from the Simcox lab were made from docking-site flies generated by Jack Bateman's group. The 16 lines from the DGRC group were made by insertion of docking sites into two pre-existing well-characterized lines, Kc167 and Sg4. The two approaches have complementary advantages and disadvantages, which are discussed in the papers. For convenience, we have included in the Notes section of the webpage for each docking site line a URL for the pre-publication e-copy of the relevant paper.

Citing the DGRC

When publishing experiments using materials obtained from the DGRC please cite the Drosophila Genomics Resource Center, supported by NIH grant 2P40OD010949-10A1, in the acknowledgments. Your cooperation helps us when we need to renew our grant.