About the DGRC

The Drosophila Genomics Resource Center (DGRC) serves the Drosophila research community by: (a) collecting and distributing DNA clones and vectors; (b) collecting and distributing Drosophila cell lines; (c) developing and testing genomics technologies for use in Drosophila and assisting members of the research community in their use.

All orders must be initiated through this website.

cDNAs and Vectors

The DGRC has assembled a large (over 1,000,000 and expanding) inventory of DNA clones through the generosity of individual community members, the BDGP, and the CuraGen Corporation. The collection includes transformation vectors, cDNA clones, and the CuraGen yeast two-hybrid collection. Clone collections and common vectors are listed in the catalog.

All orders must be initiated through this website.

Cell Lines

The DGRC has sought to collect as many cell lines as possible representing D. melanogaster and closely related species. The collection currently includes 166 lines and will continue to grow.

Cell lines, with brief descriptions, are listed in the catalog.

All orders must be initiated through this website.

The DGRC is located within the Biology Department of Indiana University, and is supported by a grant from the National Institutes of Health (ORIP and NIGMS). The DGRC was created under the guidance of Dr Peter Cherbas and its work is directed by Dr Andrew Zelhof and an advisory board representing the Drosophila research community.


Information Regarding DGRC Fly Extract

Fly extract (FEX) is an essential component of medium for some imaginal disc lines and for ovarian cell lines. On October 1st, the DGRC began distributing FEX derived from young Oregon-R-modENCODE adult flies (RRID:BDSC_25211). We sell it in tubes of 2.5 ml (enough for 100 ml of medium for CME Cl.8+) and tubes of 10 ml (enough for 100 ml of medium for OSS or fGS/OSS). The price is $5.50/ml. In addition, there is a flat fee for packaging and dry ice ($15.00/shipment) and the Fedex shipping charge to your location.

Fly extract must be shipped on dry ice. If we do not ordinarily send dry ice shipments to your country, your order for fly extract will be blocked, you will be asked to e-mail us to see whether we can work out a means of sending a dry ice shipment to you.

Storage requirements: We store fly extract at -20°C, where it is good for at least a year. We have thawed and re-frozen tubes of extract at least once with no obvious loss of quality.


October 1st Price Increases

As of April 15th, 2018, the DGRC received notification of its NIH award renewal for the next five years. The award budget remained flat with no increase and fortunately, no reduction. Due to both inflationary factors and the increase in personnel costs, we need to raise prices on most items in the range of 10-15% to cover our operation costs. The last price increase took place in 2013. For example, the cost of a single DNA clone now changes from $38 to $43. In comparison, a single DNA clone from Addgene is priced at $65 (another reason to send your DNA clones to the DGRC). We hope this increase does not put an undue burden on individual laboratories. We thank you for your support and will continue to serve the Drosophila community in the most efficient manner.

Citing the DGRC

When publishing experiments using materials obtained from the DGRC please cite the Drosophila Genomics Resource Center, supported by NIH grant 2P40OD010949, in the acknowledgments. Your cooperation helps us when we need to renew our grant.