For information on additional isolates of S2, see the following
    S2-DRSC | Sg4 | S2R+ | S2 unspecified


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    Flybase
    Pubmed
  • Parks et al., 2000, Development 127(7): 1373--1385
    Ligand endocytosis drives receptor dissociation and activation in the Notch pathway.
    • Keywords:
    • Notch signalling
    • Flybase
    Pubmed
  • Mishra-Gorur et al., 2002, J. Cell Biol. 159(2): 313--324
    Down-regulation of Delta by proteolytic processing.
    • Keywords:
    • Notch signalling
    • Flybase
    Pubmed
  • Bland et al., 2003, J. Biol. Chem. 278(16): 13607--13610
    Notch-induced proteolysis and nuclear localization of the Delta ligand.
    • Keywords:
    • Notch signalling
    • Flybase
    Pubmed
  • Delwig et al., 2006, Exp. Cell Res. 312(8): 1345--1360
    Endocytosis-independent mechanisms of Delta ligand proteolysis.
    • Keywords:
    • endocytosis
    • Notch signalling
    • Flybase
    Pubmed
  • Delwig and Rand, 2008, Cell. Molec. Life Sci. 65(14): 2232--2243
    Kuz and TACE can activate Notch independent of ligand.
    • Keywords:
    • Notch signalling
    • Flybase
    Pubmed
  • Lake et al., 2009, PLoS ONE 4(8): e6728
    In vivo analysis of the Notch receptor S1 cleavage.
    • Keywords:
    • Notch signalling
    • Flybase
    Pubmed
  • Auer et al., 2015, Cell. Signal. 27(1): 115--124
    MAPK-dependent phosphorylation modulates the activity of Suppressor of Hairless in Drosophila.
    • Keywords:
    • Notch signalling