-
Schneider, 1972, J. Embryol. exp. Morphol. 27: 353--365
Cell lines derived from late embryonic stages of Drosophila melanogaster.
-
Fehon et al., 1990, Cell 61: 523--534
Molecular interactions between the protein products of the neurogenic loci Notch and Delta, two EGF-homologous genes in Drosophila.
-
Krantz and Zipursky, 1990, EMBO J. 9(6): 1969--1977
Drosophila chaoptin, a member of the leucine-rich repeat family, is a photoreceptor cell-specific adhesion molecule.
-
Doctor et al., 1991, Mol. Cell. Biol. 11: 2319--2323
Identification of a fibroblast growth factor-binding protein in Drosophila melanogaster.
-
Kramer et al., 1991, Nature 352: 207--212
Interaction of bride of sevenless membrane-bound ligand and the sevenless tyrosine-kinase receptor.
-
Ayer and Benyajati, 1992, Mol. Cell. Biol. 12(2): 661--673
The binding site of a steroid hormone receptor-like protein within the Drosophila Adh adult enhancer is required for high levels of tissue-specific Alcohol dehydrogenase expression.
-
Nose et al., 1992, Cell 70(4): 553--567
Connectin: a homophilic cell adhesion molecule expressed on a subset of muscles and the motoneurons that innervate them in Drosophila.
-
Matunis et al., 1992, J. Cell Biol. 116: 245--255
Isolation of hnRNP complexes from Drosophila melanogaster.
-
Kania et al., 1993, Neuron 11(4): 673--687
neuromusculin, a Drosophila gene expressed in peripheral neuronal precursors and muscles, encodes a cell adhesion molecule.
-
Gertler et al., 1995, Genes Dev. 9(5): 521--533
enabled, a dosage-sensitive suppressor of mutations in the Drosophila Abl tyrosine kinase, encodes an Abl substrate with SH3 domain-binding properties.
-
Schneider et al., 1995, Neuron 15(2): 259--271
Restricted expression of the irreC-rst protein is required for normal axonal projections of columnar visual neurons.
-
Fisher et al., 1996, Mol. Cell. Biol. 16(6): 2670--2677
The WRPW motif of the hairy-related basic helix-loop-helix repressor proteins acts as a 4-amino-acid transcription repression and protein-protein interaction domain.
-
Bhanot et al., 1996, Nature 382(6588): 225--230
A new member of the frizzled family from Drosophila functions as a wingless receptor.
-
Clemens et al., 1996, J. Biol. Chem. 271(29): 17002--17005
A Drosophila protein-tyrosine phosphatase associates with an adapter protein required for axonal guidance.
-
Tang et al., 1997, Cell 90(3): 459--467
PHYL acts to down-regulate TTK88, a transcriptional repressor of neuronal cell fates, by a SINA-dependent mechanism.
-
Aronson et al., 1997, Mol. Cell. Biol. 17(9): 5581--5587
Groucho-dependent and -independent repression activities of Runt domain proteins.
-
Butler et al., 1997, Development 124(4): 781--792
klingon, a novel member of the Drosophila immunoglobulin superfamily, is required for the development of the R7 photoreceptor neuron.
-
Vilalta et al., 1997, J. Biol. Chem. 272(29): 18087--18092
An RNA polymerase III-defective mutation in TATA-binding protein disrupts its interaction with a transcription factor IIIB subunit in Drosophila cells.
-
Iwai et al., 1997, Neuron 19(1): 77--89
Axon patterning requires DN-cadherin, a novel neuronal adhesion receptor, in the Drosophila embryonic CNS.
-
Stark et al., 1997, Development 124(22): 4583--4594
A novel alpha integrin subunit associates with betaPS and functions in tissue morphogenesis and movement during Drosophila development.
-
Robbins et al., 1997, Cell 90(2): 225--234
Hedgehog elicits signal transduction by means of a large complex containing the kinesin-related protein costal2.
-
Copps et al., 1998, EMBO J. 17(18): 5409--5417
Complex formation by the Drosophila MSL proteins: role of the MSL2 RING finger in protein complex assembly.
-
Cherbas and Cherbas, 1998, Roberts, 1998: 319--346
Cell culture.
-
Le and Simon, 1998, Mol. Cell. Biol. 18(8): 4844--4854
Disabled is a putative adaptor protein that functions during signaling by the sevenless receptor tyrosine kinase.
-
Kennedy et al., 1998, Mol. Cell. Biol. 18(9): 5425--5434
A role for SRp54 during intron bridging of small introns with pyrimidine tracts upstream of the branch point.
-
Comer et al., 1998, Mol. Cell. Biol. 18(1): 152--160
Phosphorylation of Enabled by the Drosophila Abelson tyrosine kinase regulates the in vivo function and protein-protein interactions of Enabled.
-
Ahern-Djamali et al., 1998, Mol. Biol. Cell 9(8): 2157--2171
Mutations in Drosophila enabled and rescue by human vasodilator-stimulated phosphoprotein (VASP) indicate important functional roles for Ena/VASP homology domain 1 (EVH1) and EVH2 domains.
-
Collins et al., 1999, EMBO J. 18(24): 7029--7040
Osa associates with the Brahma chromatin remodeling complex and promotes the activation of some target genes.
-
Hing et al., 1999, Cell 97(7): 853--863
Pak functions downstream of Dock to regulate photoreceptor axon guidance in Drosophila.
-
Juang and Hoffmann, 1999, Oncogene 18(37): 5138--5147
Drosophila abelson interacting protein (dAbi) is a positive regulator of abelson tyrosine kinase activity.
-
Brose et al., 1999, Cell 96(6): 795--806
Slit proteins bind Robo receptors and have an evolutionarily conserved role in repulsive axon guidance.
-
Wills et al., 1999, Neuron 22(2): 301--312
The tyrosine kinase Abl and its substrate enabled collaborate with the receptor phosphatase Dlar to control motor axon guidance.
-
Kopp et al., 1999, Genes Dev. 13(16): 2059--2071
ECSIT is an evolutionarily conserved intermediate in the Toll/IL-1 signal transduction pathway.
-
Wodarz et al., 1999, Nature 402(6761): 544--547
Bazooka provides an apical cue for Inscuteable localization in Drosophila neuroblasts.
-
Von Ohlen and Hooper, 1999, Dev. Biol. 208(1): 147--156
The ciD mutation encodes a chimeric protein whose activity is regulated by wingless signaling.
-
Parks et al., 2000, Development 127(7): 1373--1385
Ligand endocytosis drives receptor dissociation and activation in the Notch pathway.
-
Wodarz et al., 2000, J. Cell Biol. 150(6): 1361--1374
Drosophila atypical protein kinase C associates with Bazooka and controls polarity of epithelia and neuroblasts.
-
Fremion et al., 2000, EMBO J. 19(17): 4463--4472
Amalgam is a ligand for the transmembrane receptor neurotactin and is required for neurotactin-mediated cell adhesion and axon fasciculation in Drosophila.
-
Jin et al., 2000, J. Cell Biol. 149(5): 1005--1010
JIL-1, a chromosomal kinase implicated in regulation of chromatin structure, associates with the male specific lethal (MSL) dosage compensation complex.
-
Smith et al., 2000, Mol. Cell. Biol. 20(1): 312--318
The Drosophila MSL complex acetylates histone H4 at lysine 16, a chromatin modification linked to dosage compensation.
-
Rorth et al., 2000, Mol. Cell 6(1): 23--30
The level of C/EBP protein is critical for cell migration during Drosophila oogenesis and is tightly controlled by regulated degradation.
-
Schmucker et al., 2000, Cell 101(6): 671--684
Drosophila Dscam is an axon guidance receptor exhibiting extraordinary molecular diversity.
-
Johnson et al., 2000, Mol. Cell 6(2): 467--478
In vivo functions of the Patched protein: requirement of the C terminus for target gene inactivation but not Hedgehog sequestration.
-
Bashaw et al., 2000, Cell 101(7): 703--715
Repulsive axon guidance: abelson and enabled play opposing roles downstream of the roundabout receptor.
-
Crevel et al., 2001, J. Cell Sci. 114(11): 2015--2025
The Drosophila Dpit47 protein is a nuclear Hsp90 co-chaperone that interacts with DNA polymerase .
-
Lorenzen et al., 2001, Development 128(8): 1403--1414
Nuclear import of activated D-ERK by DIM-7, an importin family member encoded by the gene moleskin.
-
Scaerou et al., 2001, J. Cell Sci. 114(17): 3103--3114
The ZW10 and Rough Deal checkpoint proteins function together in a large, evolutionarily conserved complex targeted to the kinetochore.
-
Dworak et al., 2001, Development 128(21): 4265--4276
Characterization of Drosophila hibris, a gene related to human nephrin.
-
Moberg et al., 2001, Nature 413(6853): 311--316
Archipelago regulates Cyclin E levels in Drosophila and is mutated in human cancer cell lines.
-
Hammond et al., 2001, Science 293(5532): 1146--1150
Argonaute2, a link between genetic and biochemical analyses of RNAi.
-
Ballestar et al., 2001, Europ. J. Biochem. 268(20): 5397--5406
A Drosophila MBD family member is a transcriptional corepressor associated with specific genes.
-
Gao and Pan, 2001, Genes Dev. 15(11): 1383--1392
TSC1 and TSC2 tumor suppressors antagonize insulin signaling in cell growth.
-
Kitagawa et al., 2001, Mol. Cell. Biol. 21(13): 4337--4346
A human protein with sequence similarity to Drosophila mastermind coordinates the nuclear form of notch and a CSL protein to build a transcriptional activator complex on target promoters.
-
Worby et al., 2001, J. Biol. Chem. 276(45): 41782--41789
The sorting nexin, DSH3PX1, connects the axonal guidance receptor, Dscam, to the actin cytoskeleton.
-
Chen and Olson, 2001, Dev. Cell 1(5): 705--715
Antisocial, an intracellular adaptor protein, is required for myoblast fusion in Drosophila.
-
Lee et al., 2001, Cell 107(2): 161--171
Regulated intracellular ligand transport and proteolysis control EGF signal activation in Drosophila.
-
Mishra-Gorur et al., 2002, J. Cell Biol. 159(2): 313--324
Down-regulation of Delta by proteolytic processing.
-
Worby et al., 2002, J. Biol. Chem. 277(11): 9422--9428
Drosophila Ack targets its substrate, the sorting nexin DSH3PX1, to a protein complex involved in axonal guidance.
-
Radford et al., 2002, J. Biol. Chem. 277(41): 38810--38817
Systematic G-protein-coupled receptor analysis in Drosophila melanogaster identifies a leucokinin receptor with novel roles.
-
Gao et al., 2002, Nat. Cell Biol. 4(9): 699--704
Tsc tumour suppressor proteins antagonize amino-acid-TOR signalling.
-
Caudy et al., 2002, Genes Dev. 16(19): 2491--2496
Fragile X-related protein and VIG associate with the RNA interference machinery.
-
Ishizuka et al., 2002, Genes Dev. 16(19): 2497--2508
A Drosophila fragile X protein interacts with components of RNAi and ribosomal proteins.
-
Yildiz et al., 2002, Mol. Cell 10(6): 1503--1509
Drosophila MUS312 interacts with the nucleotide excision repair endonuclease MEI-9 to generate meiotic crossovers.
-
Pagans et al., 2002, Nucleic Acids Res. 30(20): 4406--4413
The Drosophila transcription factor tramtrack (TTK) interacts with Trithorax-like (GAGA) and represses GAGA-mediated activation.
-
Kanda et al., 2002, J. Biol. Chem. 277(32): 28372--28375
Wengen, a Member of the Drosophila Tumor Necrosis Factor Receptor Superfamily, Is Required for Eiger Signaling.
-
Urban et al., 2002, EMBO J. 21(16): 4277--4286
A family of Rhomboid intramembrane proteases activates all Drosophila membrane-tethered EGF ligands.
-
Tanaka et al., 2002, J. Biol. Chem. 277(15): 12816--12823
Drosophila segment polarity gene product porcupine stimulates the posttranslational N-glycosylation of wingless in the endoplasmic reticulum.
-
Wills et al., 2002, Neuron 36(4): 611--622
A Drosophila homolog of cyclase-associated proteins collaborates with the abl tyrosine kinase to control midline axon pathfinding.
-
Mihaylov et al., 2002, Mol. Cell. Biol. 22(6): 1868--1880
Control of DNA replication and chromosome ploidy by geminin and cyclin a.
-
Hays et al., 2002, Nat. Cell Biol. 4(6): 425--431
Morgue mediates apoptosis in the Drosophila melanogaster retina by promoting degradation of DIAP1.
-
Wu and Nusse, 2002, J. Biol. Chem. 277(44): 41762--41769
Ligand receptor interactions in the Wnt signaling pathway in Drosophila.
-
Myat et al., 2002, Neuron 35(3): 447--459
Drosophila nedd4, a ubiquitin ligase, is recruited by commissureless to control cell surface levels of the roundabout receptor.
-
Bland et al., 2003, J. Biol. Chem. 278(16): 13607--13610
Notch-induced proteolysis and nuclear localization of the Delta ligand.
-
Hashimoto et al., 2003, Dev. Cell 5(6): 945--950
Spatial regulation of developmental signaling by a serpin.
-
Jia et al., 2003, Genes Dev. 17(21): 2709--2720
Smoothened transduces Hedgehog signal by physically interacting with Costal2/Fused complex through its C-terminal tail.
-
Liebl et al., 2003, Development 130(14): 3217--3226
Interactions between the secreted protein Amalgam, its transmembrane receptor Neurotactin and the Abelson tyrosine kinase affect axon pathfinding.
-
Stark et al., 2003, PLoS Biol. 1(3): e60
Identification of Drosophila microRNA targets.
-
Betschinger et al., 2003, Nature 422(6929): 326--330
The Par complex directs asymmetric cell division by phosphorylating the cytoskeletal protein Lgl.
-
Pantalacci et al., 2003, Nat. Cell Biol. 5(10): 921--927
The Salvador partner Hippo promotes apoptosis and cell-cycle exit in Drosophila.
-
Subramanian et al., 2003, Curr. Biol. 13(13): 1086--1095
Shortstop recruits EB1/APC1 and promotes microtubule assembly at the muscle-tendon junction.
-
Liu et al., 2003, Science 301(5641): 1921--1925
R2D2, a bridge between the initiation and effector steps of the Drosophila RNAi pathway.
-
Lum et al., 2003, Mol. Cell 12(5): 1261--1274
Hedgehog signal transduction via Smoothened association with a cytoplasmic complex scaffolded by the atypical kinesin, Costal-2.
-
Higa et al., 2003, Nat. Cell Biol. 5(11): 1008--1015
Radiation-mediated proteolysis of CDT1 by CUL4-ROC1 and CSN complexes constitutes a new checkpoint.
-
Ruel et al., 2003, Nat. Cell Biol. 5(10): 907--913
Stability and association of Smoothened, Costal2 and Fused with Cubitus interruptus are regulated by Hedgehog.
-
Caudy et al., 2003, Nature 425(6956): 411--414
A micrococcal nuclease homologue in RNAi effector complexes.
-
Wu et al., 2003, Cell 114(4): 445--456
hippo encodes a Ste-20 family protein kinase that restricts cell proliferation and promotes apoptosis in conjunction with salvador and warts.
-
Weber et al., 2003, Nat. Immunol. 4(8): 794--800
Binding of the Drosophila cytokine Spatzle to Toll is direct and establishes signaling.
-
Kusch et al., 2003, Mol. Cell. Biol. 23(9): 3305--3319
Two Drosophila Ada2 homologues function in different multiprotein complexes.
-
Islam et al., 2003, Development 130(10): 2051--2059
Neuroglian activates Echinoid to antagonize the Drosophila EGF receptor signaling pathway.
-
Terada et al., 2003, J. Cell Biol. 162(5): 757--764
Interaction of Aurora-A and centrosomin at the microtubule-nucleating site in Drosophila and mammalian cells.
-
Jia et al., 2003, Genes Dev. 17(20): 2514--2519
The Drosophila Ste20 family kinase dMST functions as a tumor suppressor by restricting cell proliferation and promoting apoptosis.
-
Pomar et al., 2003, Europ. J. Biochem. 270(2): 293--306
Functional characterization of Drosophila melanogaster PERK eukaryotic initiation factor 2alpha (eIF2alpha) kinase.
-
Nelson et al., 2004, EMBO J. 23(1): 150--159
Drosophila Cup is an eIF4E-binding protein that functions in Smaug-mediated translational repression.
-
Matakatsu and Blair, 2004, Development 131(15): 3785--3794
Interactions between Fat and Dachsous and the regulation of planar cell polarity in the Drosophila wing.
-
Okamura et al., 2004, Genes Dev. 18(14): 1655--1666
Distinct roles for Argonaute proteins in small RNA-directed RNA cleavage pathways.
-
Kusch et al., 2004, Science 306: 2084--2087
Acetylation by Tip60 Is Required for Selective Histone Variant Exchange at DNA Lesions.
-
Li et al., 2004, Mol. Cell. Biol. 24(5): 1897--1906
Architectural arrangement of cloned proximal sequence element-binding protein subunits on Drosophila U1 and U6 snRNA gene promoters.
-
Korenjak et al., 2004, Cell 119(2): 181--193
Native E2F/RBF complexes contain Myb-interacting proteins and repress transcription of developmentally controlled E2F target genes.
-
Denli et al., 2004, Nature 432(7014): 231--235
Processing of primary microRNAs by the Microprocessor complex.
-
Rehwinkel et al., 2004, Nat. Struct. Mol. Biol. 11(6): 558--566
Genome-wide analysis of mRNAs regulated by the THO complex in Drosophila melanogaster.
-
Wojtowicz et al., 2004, Cell 118(5): 619--633
Alternative splicing of Drosophila Dscam generates axon guidance receptors that exhibit isoform-specific homophilic binding.
-
Galletta et al., 2004, Mech. Dev. 121(12): 1455--1468
SNS: adhesive properties, localization requirements and ectodomain dependence in S2 cells and embryonic myoblasts.
-
Wilkin et al., 2004, Curr. Biol. 14(24): 2237--2244
Regulation of Notch endosomal sorting and signaling by Drosophila Nedd4 family proteins.
-
Le Gall and Giniger, 2004, J. Biol. Chem. 279(28): 29418--29426
Identification of two binding regions for the suppressor of hairless protein within the intracellular domain of Drosophila Notch.
-
Temme et al., 2004, EMBO J. 23(14): 2862--2871
A complex containing the CCR4 and CAF1 proteins is involved in mRNA deadenylation in Drosophila.
-
Sakata et al., 2004, Curr. Biol. 14(24): 2228--2236
Drosophila Nedd4 regulates endocytosis of Notch and suppresses its ligand-independent activation.
-
Bogdan et al., 2005, Nat. Cell Biol. 7(10): 977--984
Abi activates WASP to promote sensory organ development.
-
Hutterer and Knoblich, 2005, EMBO Rep. 6(9): 836--842
Numb and alpha-Adaptin regulate Sanpodo endocytosis to specify cell fate in Drosophila external sensory organs.
-
von Stein et al., 2005, Development 132(7): 1675--1686
Direct association of Bazooka/PAR-3 with the lipid phosphatase PTEN reveals a link between the PAR/aPKC complex and phosphoinositide signaling.
-
Arquier et al., 2005, Curr. Biol. 15(1): 19--23
Drosophila Lk6 kinase controls phosphorylation of eukaryotic translation initiation factor 4E and promotes normal growth and development.
-
Miyoshi et al., 2005, Genes Dev. 19(23): 2837--2848
Slicer function of Drosophila Argonautes and its involvement in RISC formation.
-
Sevrioukov et al., 2005, Mol. Biol. Cell 16(5): 2301--2312
A mutation in dVps28 reveals a link between a subunit of the endosomal sorting complex required for transport-I complex and the actin cytoskeleton in Drosophila.
-
Forstemann et al., 2005, PLoS Biol. 3(7): e236
Normal microRNA maturation and germ-line stem cell maintenance requires Loquacious, a double-stranded RNA-binding domain protein.
-
Chang and Min, 2005, Nat. Neurosci. 8(11): 1577--1585
Drosophila melanogaster homolog of Down syndrome critical region 1 is critical for mitochondrial function.
-
Djiane et al., 2005, Cell 121(4): 621--631
The apical determinants aPKC and dPatj regulate Frizzled-dependent planar cell polarity in the Drosophila eye.
-
Saito et al., 2005, PLoS Biol. 3(7): e235
Processing of pre-microRNAs by the Dicer-1-Loquacious complex in Drosophila cells.
-
Jekely et al., 2005, Dev. Cell 9(2): 197--207
Regulators of endocytosis maintain localized receptor tyrosine kinase signaling in guided migration.
-
Mutsuddi et al., 2005, Genetics 170(2): 687--695
Using Drosophila to decipher how mutations associated with human branchio-oto-renal syndrome and optical defects compromise the protein tyrosine phosphatase and transcriptional functions of eyes absent.
-
Forsthoefel et al., 2005, Development 132(8): 1983--1994
The Abelson tyrosine kinase, the Trio GEF and Enabled interact with the Netrin receptor Frazzled in Drosophila.
-
Kwon et al., 2005, Proc. Natl. Acad. Sci. U.S.A. 102(52): 18986--18991
MicroRNA1 influences cardiac differentiation in Drosophila and regulates Notch signaling.
-
Parra-Palau et al., 2005, Biochem. J. 385(3): 695--702
The Drosophila protein kinase LK6 is regulated by ERK and phosphorylates the eukaryotic initiation factor eIf4E in vivo.
-
Betschinger et al., 2005, Curr. Biol. 15(3): 276--282
Phosphorylation-induced autoinhibition regulates the cytoskeletal protein Lethal (2) giant larvae.
-
Jiang et al., 2005, Genes Dev. 19(14): 1674--1679
Dicer-1 and R3D1-L catalyze microRNA maturation in Drosophila.
-
Huang et al., 2005, Cell 122(3): 421--434
The Hippo signaling pathway coordinately regulates cell proliferation and apoptosis by inactivating Yorkie, the Drosophila Homolog of YAP.
-
Burgler and Macdonald, 2005, BMC Genomics 6(1): 88
Prediction and verification of microRNA targets by MovingTargets, a highly adaptable prediction method.
-
Ashley et al., 2005, J. Neurosci. 25(25): 5943--5955
Fasciclin II signals new synapse formation through amyloid precursor protein and the scaffolding protein dX11/Mint.
-
Robins et al., 2005, Proc. Natl. Acad. Sci. U.S.A. 102(11): 4006--4009
Incorporating structure to predict microRNA targets.
-
Geuking et al., 2005, Genetics 171(4): 1683--1694
A genetic screen targeting the tumor necrosis factor/Eiger signaling pathway: identification of Drosophila TAB2 as a functionally conserved component.
-
Delwig et al., 2006, Exp. Cell Res. 312(8): 1345--1360
Endocytosis-independent mechanisms of Delta ligand proteolysis.
-
Mosimann et al., 2006, Cell 125(2): 327--341
Parafibromin/Hyrax activates Wnt/Wg target gene transcription by direct association with beta-catenin/Armadillo.
-
Guelman et al., 2006, Mol. Cell. Biol. 26(3): 871--882
Host cell factor and an uncharacterized SANT domain protein are stable components of ATAC, a novel dAda2A/dGcn5-containing histone acetyltransferase complex in Drosophila.
-
Serpe and O'Connor, 2006, Development 133(24): 4969--4979
The metalloprotease tolloid-related and its TGF-beta-like substrate Dawdle regulate Drosophila motoneuron axon guidance.
-
Hutterer et al., 2006, Dev. Cell 11(2): 147--157
Mitotic activation of the kinase Aurora-A requires its binding partner Bora.
-
Cho et al., 2006, Nat. Genet. 38(10): 1142--1150
Delineation of a Fat tumor suppressor pathway.
-
Lu et al., 2006, Genes Dev. 20(18): 2539--2551
The C-terminal tail of the Hedgehog receptor Patched regulates both localization and turnover.
-
Johnson et al., 2006, Neuron 49(4): 517--531
The HSPGs Syndecan and Dallylike bind the receptor phosphatase LAR and exert distinct effects on synaptic development.
-
Teleman and Cohen, 2006, Genes Dev. 20(4): 417--422
Drosophila lacking microRNA miR-278 are defective in energy homeostasis.
-
Smelkinson and Kalderon, 2006, Curr. Biol. 16(1): 110--116
Processing of the Drosophila hedgehog signalling effector Ci-155 to receptor Ci-75 is mediated by direct binding to the SCF component slimb.
-
Miura et al., 2006, Dev. Cell 10(2): 167--176
Palmitoylation of the EGFR ligand Spitz by Rasp increases Spitz activity by restricting its diffusion.
-
Balagopalan et al., 2006, Mol. Cell. Biol. 26(24): 9442--9455
The CDM superfamily protein MBC directs myoblast fusion through a mechanism that requires phosphatidylinositol 3,4,5-triphosphate binding but is independent of direct interaction with DCrk.
-
Ruike et al., 2006, FEBS J. 273(22): 5062--5073
Characterization of a second proliferating cell nuclear antigen (PCNA2) from Drosophila melanogaster.
-
Tsuda et al., 2006, EMBO J. 25(13): 3191--3202
An NRSF/REST-like repressor downstream of Ebi/SMRTER/Su(H) regulates eye development in Drosophila.
-
Furuyama et al., 2006, Proc. Natl. Acad. Sci. U.S.A. 103(16): 6172--6177
Chaperone-mediated assembly of centromeric chromatin in vitro.
-
Gallet et al., 2006, Development 133(3): 407--418
Cholesterol modification is necessary for controlled planar long-range activity of Hedgehog in Drosophila epithelia.
-
Li et al., 2006, Genes Dev. 20(20): 2793--2805
MicroRNA-9a ensures the precise specification of sensory organ precursors in Drosophila.
-
Furuyama and Henikoff, 2006, Cell Cycle 5(12): 1269--1274
Biotin-tag affinity purification of a centromeric nucleosome assembly complex.
-
Ataman et al., 2006, Proc. Natl. Acad. Sci. U.S.A. 103(20): 7841--7846
Nuclear trafficking of Drosophila Frizzled-2 during synapse development requires the PDZ protein dGRIP.
-
Speder et al., 2006, Nature 440(7085): 803--807
Type ID unconventional myosin controls left-right asymmetry in Drosophila.
-
Tie et al., 2007, Mol. Cell. Biol. 27(6): 2014--2026
The N terminus of Drosophila ESC binds directly to histone H3 and is required for E(Z)-dependent trimethylation of H3 lysine 27.
-
Millard et al., 2007, Nature 447(7145): 720--724
Dscam2 mediates axonal tiling in the Drosophila visual system.
-
Kertesz et al., 2007, Nat. Genet. 39(10): 1278--1284
The role of site accessibility in microRNA target recognition.
-
D'Avino et al., 2007, PLoS ONE 2(6): e572
Recruitment of Polo kinase to the spindle midzone during cytokinesis requires the Feo/Klp3A complex.
-
Andersen and Leevers, 2007, J. Biol. Chem. 282(20): 14752--14760
The essential Drosophila ATP-binding cassette domain protein, pixie, binds the 40 S ribosome in an ATP-dependent manner and is required for translation initiation.
-
Liu et al., 2007, Genes Dev. 21(15): 1949--1963
Fused-Costal2 protein complex regulates Hedgehog-induced Smo phosphorylation and cell-surface accumulation.
-
Lee et al., 2007, Development 134(9): 1767--1777
The F-actin-microtubule crosslinker Shot is a platform for Krasavietz-mediated translational regulation of midline axon repulsion.
-
Secombe et al., 2007, Genes Dev. 21(5): 537--551
The Trithorax group protein Lid is a trimethyl histone H3K4 demethylase required for dMyc-induced cell growth.
-
Qurashi et al., 2007, Neural Dev. 2: 18
HSPC300 and its role in neuronal connectivity.
-
Chen et al., 2007, Curr. Biol. 17(4): 293--303
Multiple protein phosphatases are required for mitosis in Drosophila.
-
Bejarano et al., 2007, EMBO Rep. 8(8): 778--783
Hedgehog restricts its expression domain in the Drosophila wing.
-
Beltran et al., 2007, Genome Biol. 8(4): R67
Functional dissection of the ash2 and ash1 transcriptomes provides insights into the transcriptional basis of wing phenotypes and reveals conserved protein interactions.
-
Arama et al., 2007, PLoS Biol. 5(10): e251
A ubiquitin ligase complex regulates caspase activation during sperm differentiation in Drosophila.
-
Huang et al., 2007, J. Biol. Chem. 282(44): 32442--32452
The involvement of Abl and PTP61F in the regulation of Abi protein localization and stability and lamella formation in Drosophila S2 cells.
-
Förstemann et al., 2007, Cell 130(2): 287--297
Drosophila microRNAs are sorted into functionally distinct argonaute complexes after production by Dicer-1.
-
Lee et al., 2007, Mol. Cells 24(3): 445--451
Translation initiation factor 4E (eIF4E) is regulated by cell death inhibitor, Diap1.
-
Silver et al., 2007, Proc. Natl. Acad. Sci. U.S.A. 104(46): 18151--18156
Functional screening identifies miR-315 as a potent activator of Wingless signaling.
-
Karres et al., 2007, Cell 131(1): 136--145
The conserved microRNA MiR-8 tunes atrophin levels to prevent neurodegeneration in drosophila.
-
Ye et al., 2007, J. Biol. Chem. 282(39): 28373--28378
Functional anatomy of the Drosophila MicroRNA- generating enzyme.
-
Przewloka et al., 2007, PLoS ONE 2(5): e478
Molecular analysis of core kinetochore composition and assembly in Drosophila melanogaster.
-
Varghese and Cohen, 2007, Genes Dev. 21(18): 2277--2282
microRNA miR-14 acts to modulate a positive autoregulatory loop controlling steroid hormone signaling in Drosophila.
-
Thermann and Hentze, 2007, Nature 447(7146): 875--878
Drosophila miR2 induces pseudo-polysomes and inhibits translation initiation.
-
Schnorrer et al., 2007, Dev. Cell 12(5): 751--766
The transmembrane protein kon-tiki couples to Dgrip to mediate myotube targeting in Drosophila.
-
Vaziri et al., 2008, Proc. Natl. Acad. Sci. U.S.A. 105(51): 20221--20226
Multilayer three-dimensional super resolution imaging of thick biological samples.
-
Helsten et al., 2008, Mol. Biol. Cell 19(8): 3589--3598
Differences in regulation of Drosophila and vertebrate integrin affinity by talin.
-
Kurzhals et al., 2008, Dev. Biol. 313(1): 293--306
Drosophila ESC-like can substitute for ESC and becomes required for Polycomb silencing if ESC is absent.
-
Delwig and Rand, 2008, Cell. Molec. Life Sci. 65(14): 2232--2243
Kuz and TACE can activate Notch independent of ligand.
-
Tanaka et al., 2008, Mol. Cell. Biol. 28(5): 1616--1629
Myocyte enhancer factor 2 and chorion factor 2 collaborate in activation of the myogenic program in Drosophila.
-
Iklé et al., 2008, Dev. Dyn. 237(8): 2090--2099
Cardiac expression of the Drosophila Transglutaminase (CG7356) gene is directly controlled by myocyte enhancer factor-2.
-
Spresser et al., 2008, J. Genet. 87(2): 109--117
Characterization of gene expression regulated by human OTK18 using Drosophila melanogaster as a model system for innate immunity.
-
Stephan et al., 2008, Mech. Dev. 125(3-4): 183--195
Abi induces ectopic sensory organ formation by stimulating EGFR signaling.
-
Stark et al., 2008, Genes Dev. 22(1): 8--13
A single Hox locus in Drosophila produces functional microRNAs from opposite DNA strands.
-
Thompson and Travers, 2008, PLoS ONE 3(8): e3008
A Drosophila Smyd4 homologue is a muscle-specific transcriptional modulator involved in development.
-
D'Avino et al., 2008, J. Cell Sci. 121(8): 1151--1158
Interaction between Anillin and RacGAP50C connects the actomyosin contractile ring with spindle microtubules at the cell division site.
-
Wu and Mlodzik, 2008, Dev. Cell 15(3): 462--469
The frizzled extracellular domain is a ligand for Van Gogh/Stbm during nonautonomous planar cell polarity signaling.
-
Suganuma et al., 2008, Nat. Struct. Mol. Biol. 15(4): 364--372
ATAC is a double histone acetyltransferase complex that stimulates nucleosome sliding.
-
Eulalio et al., 2008, Nat. Struct. Mol. Biol. 15(4): 346--353
GW182 interaction with Argonaute is essential for miRNA-mediated translational repression and mRNA decay.
-
Whitworth et al., 2008, Dis. Model Mech. 1(2-3): 168--174
Rhomboid-7 and HtrA2/Omi act in a common pathway with the Parkinson's disease factors Pink1 and Parkin.
-
Cherbas, 2008.11.12, Cell lines from the DGRC.
Cell lines from the DGRC.
-
Liu et al., 2009, Genome Biol. 10(3): R26
Parallel RNAi screens across different cell lines identify generic and cell type-specific regulators of actin organization and cell morphology.
-
Lake et al., 2009, PLoS ONE 4(8): e6728
In vivo analysis of the Notch receptor S1 cleavage.
-
Oh et al., 2009, Dev. Biol. 335(1): 188--197
Phosphorylation-independent repression of Yorkie in Fat-Hippo signaling.
-
Tie et al., 2009, Development 136(18): 3131--3141
CBP-mediated acetylation of histone H3 lysine 27 antagonizes Drosophila Polycomb silencing.
-
Zekri et al., 2009, Mol. Cell. Biol. 29(23): 6220--6231
The silencing domain of GW182 interacts with PABPC1 to promote translational repression and degradation of microRNA targets and is required for target release.
-
Kuraishi et al., 2009, EMBO J. 28(24): 3868--3878
Pretaporter, a Drosophila protein serving as a ligand for Draper in the phagocytosis of apoptotic cells.
-
Kaido et al., 2009, Genes Cells 14(9): 1067--1077
Essential requirement for RING finger E3 ubiquitin ligase Hakai in early embryonic development of Drosophila.
-
Alarcón et al., 2009, Cell 139(4): 757--769
Nuclear CDKs drive Smad transcriptional activation and turnover in BMP and TGF-beta pathways.
-
D'Avino et al., 2009, Methods Mol. Biol. (N.Y.) 545: 99--112
Isolation of protein complexes involved in mitosis and cytokinesis from Drosophila cultured cells.
-
Miyoshi et al., 2009, RNA 15(7): 1282--1291
Characterization of the miRNA-RISC loading complex and miRNA-RISC formed in the Drosophila miRNA pathway.
-
Zhou et al., 2009, RNA 15(10): 1886--1895
Processing of Drosophila endo-siRNAs depends on a specific Loquacious isoform.
-
Koch et al., 2009, PLoS Genet. 5(9): e1000644
Windei, the Drosophila homolog of mAM/MCAF1, is an essential cofactor of the H3K9 methyl transferase dSETDB1/Eggless in germ line development.
-
Genevet et al., 2010, Dev. Cell 18(2): 300--308
Kibra is a regulator of the Salvador/Warts/Hippo signaling network.
-
Buster et al., 2010, J. Vis. Exp.:
Preparation of Drosophila S2 cells for Light Microscopy.
-
Cully et al., 2010, Mol. Cell. Biol. 30(2): 481--495
A role for p38 stress-activated protein kinase in regulation of cell growth via TORC1.
-
Schimizzi et al., 2010, PLoS ONE 5(6): e11381
Expression levels of a kinesin-13 microtubule depolymerase modulates the effectiveness of anti-microtubule agents.
-
Fishilevich et al., 2010, Dev. Dyn. 239(2): 559--573
pHMA, a pH-sensitive GFP reporter for cell engulfment, in Drosophila embryos, tissues, and cells.
-
Mukherjee and Hanley, 2010, BMC Microbiol. 10: 127
RNA interference modulates replication of dengue virus in Drosophila melanogaster cells.
-
Broemer et al., 2010, Mol. Cell 40(5): 810--822
Systematic In Vivo RNAi Analysis Identifies IAPs as NEDD8-E3 Ligases.
-
Imai et al., 2010, PLoS Genet. 6(12): e1001229
The Loss of PGAM5 Suppresses the Mitochondrial Degeneration Caused by Inactivation of PINK1 in Drosophila.
-
Xia et al., 2010, Cell 143(6): 978--990
The Fused/Smurf Complex Controls the Fate of Drosophila Germline Stem Cells by Generating a Gradient BMP Response.
-
Brittle et al., 2010, Curr. Biol. 20(9): 803--810
Four-jointed modulates growth and planar polarity by reducing the affinity of dachsous for fat.
-
Kallio et al., 2010, FASEB J. 24(11): 4467--4479
Eye transformer is a negative regulator of Drosophila JAK/STAT signaling.
-
Singh et al., 2010, Genes Dev. 24(19): 2157--2168
Abelson family kinases regulate Frizzled planar cell polarity signaling via Dsh phosphorylation.
-
Kang and Bier, 2010, Dev. Biol. 346(1): 1--10
dHIP14-dependent palmitoylation promotes secretion of the BMP antagonist Sog.
-
Spain et al., 2010, J. Biol. Chem. 285(35): 27457--27467
Drosophila SIN3 isoforms interact with distinct proteins and have unique biological functions.
-
Raffa et al., 2010, Genes Dev. 24(15): 1596--1601
Verrocchio, a Drosophila OB fold-containing protein, is a component of the terminin telomere-capping complex.
-
Tsurudome et al., 2010, Neuron 68(5): 879--893
The Drosophila miR-310 Cluster Negatively Regulates Synaptic Strength at the Neuromuscular Junction.
-
Loiseau et al., 2010, Development 137(16): 2763--2772
Drosophila PAT1 is required for Kinesin-1 to transport cargo and to maximize its motility.
-
Francis et al., 2010, Curr. Biol. 20(20): 1799--1808
dDOR Is an EcR Coactivator that Forms a Feed-Forward Loop Connecting Insulin and Ecdysone Signaling.
-
Miyoshi et al., 2010, RNA 16(3): 506--515
Molecular mechanisms that funnel RNA precursors into endogenous small-interfering RNA and microRNA biogenesis pathways in Drosophila.
-
Varghese et al., 2010, Genes Dev. 24(24): 2748--2753
Drosophila miR-14 regulates insulin production and metabolism through its target, sugarbabe.
-
Mosca and Schwarz, 2010, Nat. Neurosci. 13(8): 935--943
The nuclear import of Frizzled2-C by Importins-beta11 and alpha2 promotes postsynaptic development.
-
Alvarado et al., 2010, Cell 142(4): 568--579
Structural basis for negative cooperativity in growth factor binding to an EGF receptor.
-
Arndt et al., 2010, Curr. Biol. 20(2): 143--148
Chaperone-Assisted Selective Autophagy Is Essential for Muscle Maintenance.
-
Tastan et al., 2010, Development 137(19): 3167--3176
Drosophila Ataxin 2-binding protein 1 marks an intermediate step in the molecular differentiation of female germline cysts.
-
Huang et al., 2010, Proc. Natl. Acad. Sci. U.S.A. 107(18): 8322--8327
Endocytic pathway is required for Drosophila Toll innate immune signaling.
-
Makki et al., 2010, PLoS Biol. 8(8): e1000441
A short receptor downregulates Jak/STAT signalling to control the Drosophila cellular immune response.
-
Patil and Kai, 2010, Curr. Biol. 20(8): 724--730
Repression of Retroelements in Drosophila Germline via piRNA Pathway by the Tudor Domain Protein Tejas.
-
Kim et al., 2010, Circulation Res. 106(7): 1233--1243
Gene deletion screen for cardiomyopathy in adult Drosophila identifies a new notch ligand.
-
Quinones et al., 2010, J. Cell Biol. 189(2): 353--367
I-BAR protein antagonism of endocytosis mediates directional sensing during guided cell migration.
-
Sekyrova et al., 2010, Development 137(1): 141--150
Interaction between Drosophila bZIP proteins Atf3 and Jun prevents replacement of epithelial cells during metamorphosis.
-
Tong et al., 2010, Mol. Biol. Cell 21(5): 802--810
Numb independently antagonizes sanpodo membrane targeting and notch signaling in Drosophila sensory organ precursor cells.
-
Suganuma et al., 2010, Cell 142(5): 726--736
The ATAC acetyltransferase complex coordinates MAP kinases to regulate JNK target genes.
-
Koppen et al., 2011, Proteomics 11(22): 4397--4410
Proteomics analyses of microvesicles released by Drosophila Kc167 and S2 cells.
-
Dejima et al., 2011, J. Biol. Chem. 286(19): 17103--17111
Novel Contact-dependent Bone Morphogenetic Protein (BMP) Signaling Mediated by Heparan Sulfate Proteoglycans.
-
Jovel and Schneemann, 2011, Virology 419(1): 43--53
Molecular characterization of Drosophila cells persistently infected with Flock House virus.
-
Reddy and Irvine, 2011, Development 138(23): 5201--5212
Regulation of Drosophila glial cell proliferation by Merlin-Hippo signaling.
-
Currie et al., 2011, Mol. Biol. Cell 22(22): 4343--4361
The microtubule lattice and plus-end association of Drosophila Mini spindles is spatially regulated to fine-tune microtubule dynamics.
-
Chiu et al., 2011, Cell 145(3): 357--370
NEMO/NLK Phosphorylates PERIOD to Initiate a Time-Delay Phosphorylation Circuit that Sets Circadian Clock Speed.
-
Gautier et al., 2011, J. Cell Sci. 124(20): 3414--3427
Clathrin is required for Scar/Wave-mediated lamellipodium formation.
-
Li et al., 2011, J. Cell Biol. 193(6): 973--983
EB1 promotes microtubule dynamics by recruiting Sentin in Drosophila cells.
-
Gopalakrishnan et al., 2011, Nat. Commun. 2: 359
Sas-4 provides a scaffold for cytoplasmic complexes and tethers them in a centrosome.
-
Ardehali et al., 2011, EMBO J. 30(14): 2817--2828
Drosophila Set1 is the major histone H3 lysine 4 trimethyltransferase with role in transcription.
-
Cernilogar et al., 2011, Nature 480(7377): 391--395
Chromatin-associated RNA interference components contribute to transcriptional regulation in Drosophila.
-
Bhogal et al., 2011, Nat. Neurosci. 14(12): 1517--1524
Modulation of dADAR-dependent RNA editing by the Drosophila fragile X mental retardation protein.
-
Daskalaki et al., 2011, J. Cell Biol. 195(6): 1017--1031
Distinct intracellular motifs of Delta mediate its ubiquitylation and activation by Mindbomb1 and Neuralized.
-
Ramos et al., 2011, PLoS ONE 6(1): e16562
DNA Topoisomerase II Modulates Insulator Function in Drosophila.
-
Hartl et al., 2011, J. Neurosci. 31(44): 15660--15673
A New Prospero and microRNA-279 Pathway Restricts CO2 Receptor Neuron Formation.
-
Molnar et al., 2011, PLoS Genet. 7(3): e1001335
Role of the Drosophila non-visual ß-arrestin kurtz in hedgehog signalling.
-
Stavropoulos and Young, 2011, Neuron 72(6): 964--976
insomniac and Cullin-3 Regulate Sleep and Wakefulness in Drosophila.
-
Gangaraju et al., 2011, Nat. Genet. 43(2): 153--158
Drosophila Piwi functions in Hsp90-mediated suppression of phenotypic variation.
-
Wang et al., 2011, Dev. Cell 21(3): 520--533
An ana2/ctp/mud complex regulates spindle orientation in Drosophila neuroblasts.
-
Magico and Bell, 2011, PLoS ONE 6(6): e21431
Identification of a Classical Bipartite Nuclear Localization Signal in the Drosophila TEA/ATTS Protein Scalloped.
-
Braun et al., 2011, Mol. Cell 44(1): 120--133
GW182 proteins directly recruit cytoplasmic deadenylase complexes to miRNA targets.
-
Boggiano et al., 2011, Dev. Cell 21(5): 888--895
Tao-1 phosphorylates Hippo/MST kinases to regulate the Hippo-Salvador-Warts tumor suppressor pathway.
-
Andrejka et al., 2011, Proc. Natl. Acad. Sci. U.S.A. 108(42): 17438--17443
Animal-specific C-terminal domain links myeloblastosis oncoprotein (Myb) to an ancient repressor complex.
-
Oh and Irvine, 2011, Dev. Cell 20(1): 109--122
Cooperative Regulation of Growth by Yorkie and Mad through bantam.
-
Zhang et al., 2011, Cell Res. 21(10): 1436--1451
Transduction of the Hedgehog signal through the dimerization of Fused and the nuclear translocation of Cubitus interruptus.
-
Wee et al., 2011, J. Cell Biol. 195(3): 369--376
Canoe binds RanGTP to promote PinsTPR/Mud-mediated spindle orientation.
-
Smith et al., 2011, Mol. Cell 44(6): 954--965
The little elongation complex regulates small nuclear RNA transcription.
-
Igreja and Izaurralde, 2011, Genes Dev. 25(18): 1955--1967
CUP promotes deadenylation and inhibits decapping of mRNA targets.
-
Morikawa et al., 2011, Proc. Natl. Acad. Sci. U.S.A. 108(48): 19389--19394
Different levels of the Tripartite motif protein, Anomalies in sensory axon patterning (Asap), regulate distinct axonal projections of Drosophila sensory neurons.
-
Taliaferro et al., 2011, Genes Dev. 25(6): 608--620
Evolution of a tissue-specific splicing network.
-
Gan et al., 2011, J. Biosci., Bangalore 36(3): 425--438
The Chriz-Z4 complex recruits JIL-1 to polytene chromosomes, a requirement for interband-specific phosphorylation of H3S10.
-
Shi et al., 2011, Development 138(19): 4219--4231
The Hedgehog-induced Smoothened conformational switch assembles a signaling complex that activates Fused by promoting its dimerization and phosphorylation.
-
Rumpf et al., 2011, Development 138(6): 1153--1160
Neuronal remodeling and apoptosis require VCP-dependent degradation of the apoptosis inhibitor DIAP1.
-
Tong et al., 2011, Neuron 71(3): 447--459
Rich Regulates Target Specificity of Photoreceptor Cells and N-Cadherin Trafficking in the Drosophila Visual System via Rab6.
-
Morawe et al., 2011, J. Cell Biol. 193(1): 71--80
Loss of the extraproteasomal ubiquitin receptor Rings lost impairs ring canal growth in Drosophila oogenesis.
-
Rangone et al., 2011, PLoS Genet. 7(8): e1002225
Suppression of Scant Identifies Endos as a Substrate of Greatwall Kinase and a Negative Regulator of Protein Phosphatase 2A in Mitosis.
-
Mohan et al., 2011, Mol. Cell. Biol. 31(21): 4310--4318
The COMPASS Family of H3K4 Methylases in Drosophila.
-
Dubrovsky et al., 2011, J. Biol. Chem. 286(38): 33689--33700
The Drosophila FTZ-F1 Nuclear Receptor Mediates Juvenile Hormone Activation of E75A Gene Expression through an Intracellular Pathway.
-
Chekulaeva et al., 2011, Nat. Struct. Mol. Biol. 18(11): 1218--1226
miRNA repression involves GW182-mediated recruitment of CCR4-NOT through conserved W-containing motifs.
-
Lim et al., 2011, Nature 470(7334): 399--403
The novel gene twenty-four defines a critical translational step in the Drosophila clock.
-
Weake et al., 2011, Genes Dev. 25(14): 1499--1509
Post-transcription initiation function of the ubiquitous SAGA complex in tissue-specific gene activation.
-
Yoon et al., 2011, Nat. Cell Biol. 13(9): 1062--1069
miRNA-mediated feedback inhibition of JAK/STAT morphogen signalling establishes a cell fate threshold.
-
White et al., 2011, J. Cell Biol. 193(4): 677--694
Drosophila histone locus bodies form by hierarchical recruitment of components.
-
Seisenbacher et al., 2011, PLoS Genet. 7(8): e1002168
MK2-Dependent p38b Signalling Protects Drosophila Hindgut Enterocytes against JNK-Induced Apoptosis under Chronic Stress.
-
Przewloka et al., 2011, Curr. Biol. 21(5): 399--405
CENP-C Is a Structural Platform for Kinetochore Assembly.
-
Vallejo et al., 2011, EMBO J. 30(4): 756--769
Targeting Notch signalling by the conserved miR-8/200 microRNA family in development and cancer cells.
-
Luce-Fedrow et al., 2012 | 64; 74
-
Gilchrist et al., 2012, Genes Dev. 26(9): 933--944
Regulating the regulators: the pervasive effects of Pol II pausing on stimulus-responsive gene networks.
-
Broderick et al., 2012, PLoS ONE 7(9): e44567
Drosophila ninjurin a induces nonapoptotic cell death.
-
Lansdell et al., 2012, BMC Neurosci. 13: 73
The Drosophila nicotinic acetylcholine receptor subunits Dα5 and Dα7 form functional homomeric and heteromeric ion channels.
-
Mahapatra and Rand, 2012, Neurotoxicol. Teratol. 34(4): 387--394
Methylmercury tolerance is associated with the humoral stress factor gene Turandot A.
-
Ishikawa et al., 2012, PLoS ONE 7(8): e42988
The Raine Syndrome Protein FAM20C Is a Golgi Kinase That Phosphorylates Bio-Mineralization Proteins.
-
Busayavalasa et al., 2012, J. Cell Sci. 125(18): 4214--4218
The Nup155-mediated organisation of inner nuclear membrane proteins is independent of Nup155 anchoring to the metazoan nuclear pore complex.
-
Kallijärvi et al., 2012, PLoS ONE 7(12): e51997
Characterization of Drosophila GDNF Receptor-Like and Evidence for Its Evolutionarily Conserved Interaction with Neural Cell Adhesion Molecule (NCAM)/FasII.
-
Dornier et al., 2012, J. Cell Biol. 199(3): 481--496
TspanC8 tetraspanins regulate ADAM10/Kuzbanian trafficking and promote Notch activation in flies and mammals.
-
Peru Y Colón de Portugal et al., 2012, J. Neurosci. 32(49): 17706--17713
Adult Neuronal Arf6 Controls Ethanol-Induced Behavior with Arfaptin Downstream of Rac1 and RhoGAP18B.
-
Schoenherr et al., 2012, PLoS Genet. 8(5): e1002725
Drosophila activated cdc42 kinase has an anti-apoptotic function.
-
Tang et al., 2012, Dev. Biol. 364(1): 32--41
Roles of N-glycosylation and lipidation in Wg secretion and signaling.
-
Tan et al., 2012, PLoS Genet. 8(5): e1002681
MicroRNA-277 Modulates the Neurodegeneration Caused by Fragile X Premutation rCGG Repeats.
-
Majumdar et al., 2012, Cell 148(3): 515--529
Critical Role of Amyloid-like Oligomers of Drosophila Orb2 in the Persistence of Memory.
-
Emelyanov et al., 2012, Genes Dev. 26(6): 603--614
Identification and characterization of ToRC, a novel ISWI-containing ATP-dependent chromatin assembly complex.
-
Anand and Kai, 2012, EMBO J. 31(4): 870--882
The tudor domain protein Kumo is required to assemble the nuage and to generate germline piRNAs in Drosophila.
-
Koch et al., 2012, J. Cell Sci. 125(15): 3578--3589
Abp1 utilizes the Arp2/3 complex activator Scar/WAVE in bristle development.
-
Dottermusch-Heidel et al., 2012, Dev. Biol. 368(1): 18--27
The Arf-GEF Schizo/Loner regulates N-cadherin to induce fusion competence of Drosophila myoblasts.
-
Xia et al., 2012, PLoS Biol. 10(1): e1001238
USP8 promotes smoothened signaling by preventing its ubiquitination and changing its subcellular localization.
-
Lee et al., 2012, Biochem. Biophys. Res. Commun. 417(1): 175--181
C-terminal binding protein-mediated transcriptional repression is regulated by X-linked inhibitor of apoptosis protein.
-
Suganuma et al., 2012, Mol. Cell. Proteomics 11(5): 90--99
A Metazoan ATAC Acetyltransferase Subunit That Regulates Mitogen-activated Protein Kinase Signaling Is Related to an Ancient Molybdopterin Synthase Component.
-
Maruyama et al., 2012, Biol. Pharmaceut. Bull. 35(11): 2017--2022
RecQ5 Interacts with Rad51 and Is Involved in Resistance of Drosophila to Cisplatin Treatment.
-
Aumiller et al., 2012, RNA Biol. 9(5): 633--643
Drosophila Pur-α binds to trinucleotide-repeat containing cellular RNAs and translocates to the early oocyte.
-
Praveen et al., 2012, Cell Rep. 1(6): 624--631
A Drosophila Model of Spinal Muscular Atrophy Uncouples snRNP Biogenesis Functions of Survival Motor Neuron from Locomotion and Viability Defects.
-
Yamamoto et al., 2012, Science 338(6111): 1229--1232
A Mutation in EGF Repeat-8 of Notch Discriminates Between Serrate/Jagged and Delta Family Ligands.
-
Silva-Sousa et al., 2012, PLoS Genet. 8(12): e1003153
The Chromosomal Proteins JIL-1 and Z4/Putzig Regulate the Telomeric Chromatin in Drosophila melanogaster.
-
Laflamme et al., 2012, J. Cell Biol. 198(1): 57--67
Evi5 promotes collective cell migration through its Rab-GAP activity.
-
Pfeiffenberger and Allada, 2012, PLoS Genet. 8(10): e1003003
Cul3 and the BTB Adaptor Insomniac Are Key Regulators of Sleep Homeostasis and a Dopamine Arousal Pathway in Drosophila.
-
Mulligan et al., 2012, Proc. Natl. Acad. Sci. U.S.A. 109(2): 370--377
Secreted Wingless-interacting molecule (Swim) promotes long-range signaling by maintaining Wingless solubility.
-
Panov et al., 2012, Nucleic Acids Res. 40(6): 2445--2453
Transcription co-activator SAYP mediates the action of STAT activator.
-
Krüttner et al., 2012, Neuron 76(2): 383--395
Drosophila CPEB Orb2A Mediates Memory Independent of Its RNA-Binding Domain.
-
Hayashi et al., 2012, Development 139(22): 4162--4171
Glypicans regulate JAK/STAT signaling and distribution of the Unpaired morphogen.
-
Christis and Munro, 2012, J. Cell Biol. 196(3): 327--335
The small G protein Arl1 directs the trans-Golgi-specific targeting of the Arf1 exchange factors BIG1 and BIG2.
-
Luo and Sehgal, 2012, Cell 148(4): 765--779
Regulation of Circadian Behavioral Output via a MicroRNA-JAK/STAT Circuit.
-
Belozerov et al., 2012, Mol. Cell. Biol. 32(18): 3695--3706
High-Resolution Protein Interaction Map of the Drosophila melanogaster p38 Mitogen-Activated Protein Kinases Reveals Limited Functional Redundancy.
-
Dodson et al., 2012, Hum. Mol. Genet. 21(6): 1350--1363
Roles of the Drosophila LRRK2 homolog in Rab7-dependent lysosomal positioning.
-
Takács et al., 2012, Int. J. Biol. Sci. 8(7): 1055--1061
Protein interactions on telomeric retrotransposons in Drosophila.
-
Poernbacher et al., 2012, Curr. Biol. 22(5): 389--396
Drosophila Pez acts in hippo signaling to restrict intestinal stem cell proliferation.
-
Stephan et al., 2012, J. Neurosci. 32(46): 16080--16094
Drosophila Psidin Regulates Olfactory Neuron Number and Axon Targeting through Two Distinct Molecular Mechanisms.
-
Jin et al., 2012, J. Biol. Chem. 287(8): 5784--5796
Dimerization and cytoplasmic localization regulate Hippo kinase signaling activity in organ size control.
-
Fan et al., 2012, Dev. Biol. 366(2): 172--184
Hh-induced Smoothened conformational switch is mediated by differential phosphorylation at its C-terminal tail in a dose- and position-dependent manner.
-
Fischer et al., 2012, PLoS ONE 7(8): e42349
fussel (fuss) - A Negative Regulator of BMP Signaling in Drosophila melanogaster.
-
Del Signore et al., 2012, Mech. Dev. 129(5-8): 147--161
odd-skipped genes and lines organize the notum anterior-posterior axis using autonomous and non-autonomous mechanisms.
-
Chen et al., 2012, Development 139(19): 3543--3552
miR-92b regulates Mef2 levels through a negative-feedback circuit during Drosophila muscle development.
-
Chen et al., 2012, PLoS ONE 7(9): e45094
A Role for the CAL1-Partner Modulo in Centromere Integrity and Accurate Chromosome Segregation in Drosophila.
-
Fukuyama et al., 2012, J. Proteomics 75(15): 4610--4619
On-bead tryptic proteolysis: An attractive procedure for LC-MS/MS analysis of the Drosophila caspase 8 protein complex during immune response against bacteria.
-
Petit et al., 2012, Nucleic Acids Res. 40(21): 11058--11072
The structural basis for the interaction between the CAF1 nuclease and the NOT1 scaffold of the human CCR4-NOT deadenylase complex.
-
Toledano et al., 2012, Nature 485(7400): 605--610
The let-7-Imp axis regulates ageing of the Drosophila testis stem-cell niche.
-
Insco et al., 2012, Cell Stem Cell 11(5): 689--700
A self-limiting switch based on translational control regulates the transition from proliferation to differentiation in an adult stem cell lineage.
-
Weng and Cohen, 2012, Development 139(8): 1427--1434
Drosophila miR-124 regulates neuroblast proliferation through its target anachronism.
-
Chen et al., 2012, RNA 18(12): 2148--2156
An RNAi screen identifies additional members of the Drosophila Integrator complex and a requirement for cyclin C/Cdk8 in snRNA 3'-end formation.
-
Xiong et al., 2012, PLoS Biol. 10(12): e1001438
Crag Is a GEF for Rab11 Required for Rhodopsin Trafficking and Maintenance of Adult Photoreceptor Cells.
-
Braun et al., 2012, Nat. Struct. Mol. Biol. 19(12): 1324--1331
A direct interaction between DCP1 and XRN1 couples mRNA decapping to 5' exonucleolytic degradation.
-
Bosveld et al., 2012, Science 336(6082): 724--727
Mechanical control of morphogenesis by Fat/Dachsous/Four-jointed planar cell polarity pathway.
-
Ito et al., 2012, Mol. Cell 45(4): 494--504
Epigenetic Silencing of Core Histone Genes by HERS in Drosophila.
-
Tsai et al., 2012, J. Neurosci. 32(47): 16971--16981
Neurofibromin Mediates FAK Signaling in Confining Synapse Growth at Drosophila Neuromuscular Junctions.
-
Yang et al., 2012, J. Neurosci. 32(48): 17241--17250
Drosophila vap-33 is required for axonal localization of dscam isoforms.
-
Wu et al., 2012, FEBS Lett. 586(22): 4052--4060
Drosophila miR-5 suppresses Hedgehog signaling by directly targeting Smoothened.
-
Overend et al., 2012, Peptides 34(1): 209--218
The receptor guanylate cyclase Gyc76C and a peptide ligand, NPLP1-VQQ, modulate the innate immune IMD pathway in response to salt stress.
-
Yoshiura et al., 2012, Dev. Cell 22(1): 79--91
Tre1 GPCR Signaling Orients Stem Cell Divisions in the Drosophila Central Nervous System.
-
Gurskiy et al., 2012, Nucleic Acids Res. 40(21): 10689--10700
The DUBm subunit Sgf11 is required for mRNA export and interacts with Cbp80 in Drosophila.
-
Sun et al., 2012, PLoS Genet. 8(2): e1002515
Neurophysiological Defects and Neuronal Gene Deregulation in Drosophila mir-124 Mutants.
-
Kametaka et al., 2012, J. Cell Sci. 125(3): 634--648
AP-1 clathrin adaptor and CG8538/Aftiphilin are involved in Notch signaling during eye development in Drosophila melanogaster.
-
Giagtzoglou et al., 2012, J. Cell Biol. 196(1): 65--83
dEHBP1 Controls Exocytosis and Recycling of Delta During Asymmetric Divisions.
-
Li-Kroeger et al., 2012, Development 139(9): 1611--1619
Integration of an abdominal Hox complex with Pax2 yields cell-specific EGF secretion from Drosophila sensory precursor cells.
-
Crevel et al., 2012, PLoS ONE 7(11): e49505
Drosophila RecQ4 Is Directly Involved in Both DNA Replication and the Response to UV Damage in S2 Cells.
-
Peters and Rogers, 2013, Mol. Biol. Cell 24(21): 3460--3471
Drosophila Ric-8 interacts with the Gα12/13 subunit, Concertina, during activation of the Folded gastrulation pathway.
-
Manning et al., 2013, Sci. Signal. 6(301): ra98
Regulation of epithelial morphogenesis by the g protein-coupled receptor mist and its ligand fog.
-
Applewhite et al., 2013, Mol. Biol. Cell 24(18): 2885--2893
The actin-microtubule cross-linking activity of Drosophila Short stop is regulated by intramolecular inhibition.
-
Degoutin et al., 2013, Nat. Cell Biol. 15(10): 1176--1185
Riquiqui and Minibrain are regulators of the Hippo pathway downstream of Dachsous.
-
Bosch et al., 2013, Structure 21(1): 65--75
Structural Determinants of RGS-RhoGEF Signaling Critical to Entamoeba histolytica Pathogenesis.
-
Bassi et al., 2013, Proc. Natl. Acad. Sci. U.S.A. 110(24): 9782--9787
Citron kinase controls a molecular network required for midbody formation in cytokinesis.
-
Wang et al., 2013, RNA Biol. 10(8): 1396--1406
Half pint/Puf68 is required for negative regulation of splicing by the SR splicing factor Transformer2.
-
Thomae et al., 2013, Dev. Cell 27(4): 412--424
A pair of centromeric proteins mediates reproductive isolation in Drosophila species.
-
Lim and Allada, 2013, Science 340(6134): 875--879
ATAXIN-2 activates PERIOD translation to sustain circadian rhythms in Drosophila.
-
Yang et al., 2013, J. Cell Sci. 126(18): 4230--4238
Drosophila Vps36 regulates Smo trafficking in Hedgehog signaling.
-
Amsalem et al., 2013, Mol. Cell. Biol. 33(22): 4371--4380
Drosophila oocyte polarity and cytoskeleton organization require regulation of ik2 activity by spn-f and javelin-like.
-
Cunha-Ferreira et al., 2013, Curr. Biol. 23(22): 2245--2254
Regulation of autophosphorylation controls PLK4 self-destruction and centriole number.
-
Zhang et al., 2013, J. Cell Biol. 200(6): 807--820
The C8ORF38 homologue Sicily is a cytosolic chaperone for a mitochondrial complex I subunit.
-
Huang et al., 2013, PLoS Biol. 11(8): e1001620
Par-1 regulates tissue growth by influencing hippo phosphorylation status and hippo-salvador association.
-
Fernández-Espartero et al., 2013, J. Cell Sci. 126(10): 2285--2293
GTP exchange factor Vav regulates guided cell migration by coupling guidance receptor signalling to local Rac activation.
-
Yoshigi et al., 2013, Proteome Sci. 11(1): 21
Interactions by 2D Gel Electrophoresis Overlap (iGEO): a novel high fidelity approach to identify constituents of protein complexes.
-
Harpaz et al., 2013, PLoS Genet. 9(6): e1003597
Multiplexin promotes heart but not aorta morphogenesis by polarized enhancement of slit/robo activity at the heart lumen.
-
Dui et al., 2013, Mol. Biol. Cell 24(11): 1676--1687
The Drosophila F-box protein dSkp2 regulates cell proliferation by targeting Dacapo for degradation.
-
Kyrchanova et al., 2013, PLoS Genet. 9(7): e1003606
Effective blocking of the white enhancer requires cooperation between two main mechanisms suggested for the insulator function.
-
Sabath et al., 2013, RNA 19(12): 1726--1744
3'-End processing of histone pre-mRNAs in Drosophila: U7 snRNP is associated with FLASH and polyadenylation factors.
-
Li et al., 2013, PLoS ONE 8(3): e59866
The Smc5/Smc6/MAGE Complex Confers Resistance to Caffeine and Genotoxic Stress in Drosophila melanogaster.
-
Zhang et al., 2013, Dev. Cell 25(6): 636--644
Ter94 ATPase Complex Targets K11-Linked Ubiquitinated Ci to Proteasomes for Partial Degradation.
-
Chen et al., 2013, J. Biol. Chem. 288(7): 4867--4877
Functional analysis of the integrator subunit 12 identifies a microdomain that mediates activation of the Drosophila integrator complex.
-
Taliaferro et al., 2013, Genes Dev. 27(4): 378--389
Two new and distinct roles for Drosophila Argonaute-2 in the nucleus: alternative pre-mRNA splicing and transcriptional repression.
-
Anjum et al., 2013, Genetics 195(4): 1307--1317
Regulation of Toll Signaling and Inflammation by β-Arrestin and the SUMO Protease Ulp1.
-
Padeken et al., 2013, Mol. Cell 50(2): 236--249
The Nucleoplasmin Homolog NLP Mediates Centromere Clustering and Anchoring to the Nucleolus.
-
Pan et al., 2013, Development 140(4): 831--842
Signal transduction by the Fat cytoplasmic domain.
-
McIlroy et al., 2013, Nat. Neurosci. 16(9): 1248--1256
Toll-6 and Toll-7 function as neurotrophin receptors in the Drosophila melanogaster CNS.
-
Warrington et al., 2013, Development 140(5): 1045--1054
The Frizzled-dependent planar polarity pathway locally promotes E-cadherin turnover via recruitment of RhoGEF2.
-
Fukuyama et al., 2013, Proc. Natl. Acad. Sci. U.S.A. 110(26): 10717--10722
Landscape of protein-protein interactions in Drosophila immune deficiency signaling during bacterial challenge.
-
Moshkin et al., 2013, PLoS Genet. 9(9): e1003719
Histone Chaperone NAP1 Mediates Sister Chromatid Resolution by Counteracting Protein Phosphatase 2A.
-
Takáts et al., 2013, J. Cell Biol. 201(4): 531--539
Autophagosomal Syntaxin17-dependent lysosomal degradation maintains neuronal function in Drosophila.
-
Upadhyay et al., 2013, J. Cell Biol. 201(3): 439--448
Sanpodo controls sensory organ precursor fate by directing Notch trafficking and binding γ-secretase.
-
Cotton et al., 2013, Curr. Biol. 23(7): 581--587
Numb inhibits the recycling of sanpodo in Drosophila sensory organ precursor.
-
Hong and Choi, 2013, Nat. Commun. 4: 2986
TCTP directly regulates ATM activity to control genome stability and organ development in Drosophila melanogaster.
-
Ran et al., 2013, J. Virol. 87(23): 12576--12582
White Spot Syndrome Virus IE1 and WSV056 Modulate the G1/S Transition by Binding to the Host Retinoblastoma Protein.
-
Clark and Kadrmas, 2013, Cytoskeleton (Hoboken) 70(6): 304--316
Drosophila melanogaster muscle LIM protein and alpha-actinin function together to stabilize muscle cytoarchitecture: A potential role for Mlp84B in actin-crosslinking.
-
Rougeot et al., 2013, PLoS ONE 8(10): e77592
The Elongin Complex Antagonizes the Chromatin Factor Corto for Vein versus Intervein Cell Identity in Drosophila Wings.
-
Fontenele et al., 2013, Mol. Biol. Cell 24(18): 2966--2980
Calpain A modulates Toll responses by limited Cactus/IκB proteolysis.
-
Enneking et al., 2013, PLoS Biol. 11(4): e1001537
Transsynaptic Coordination of Synaptic Growth, Function, and Stability by the L1-Type CAM Neuroglian.
-
Klebba et al., 2013, Curr. Biol. 23(22): 2255--2261
Polo-like Kinase 4 Autodestructs by Generating Its Slimb-Binding Phosphodegron.
-
Pronovost et al., 2013, PLoS Genet. 9(3): e1003406
Elevated Expression of the Integrin-Associated Protein PINCH Suppresses the Defects of Drosophila melanogaster Muscle Hypercontraction Mutants.
-
Oh et al., 2013, Cell Rep. 3(2): 309--318
Genome-wide association of Yorkie with chromatin and chromatin-remodeling complexes.
-
Fan et al., 2013, PLoS ONE 8(11): e79021
Hrs promotes ubiquitination and mediates endosomal trafficking of smoothened in Drosophila hedgehog signaling.
-
Cameron et al., 2013, J. Neurosci. 33(44): 17413--17421
Visual circuit assembly requires fine tuning of the novel Ig transmembrane protein borderless.
-
Deng et al., 2013, Dev. Biol. 375(2): 152--159
Hippo activation through homodimerization and membrane association for growth inhibition and organ size control.
-
Neisch et al., 2013, Mol. Biol. Cell 24(9): 1420--1433
Conundrum, an ARHGAP18 orthologue, regulates RhoA and proliferation through interactions with Moesin.
-
Morante et al., 2013, Dev. Cell 27(2): 174--187
Conserved miR-8/miR-200 Defines a Glial Niche that Controls Neuroepithelial Expansion and Neuroblast Transition.
-
Chang et al., 2013, Mol. Biol. Cell 24(11): 1749--1764
Normal dynactin complex function during synapse growth in Drosophila requires membrane binding by Arfaptin.
-
Takeda et al., 2013, Open Biol. 3(8): 130081
Drosophila F-BAR protein Syndapin contributes to coupling the plasma membrane and contractile ring in cytokinesis.
-
Conde et al., 2013, EMBO J. 32(12): 1761--1777
Drosophila Polo regulates the spindle assembly checkpoint through Mps1-dependent BubR1 phosphorylation.
-
Ciurciu et al., 2013, PLoS Genet. 9(10): e1003885
PNUTS/PP1 Regulates RNAPII-Mediated Gene Expression and Is Necessary for Developmental Growth.
-
Gao et al., 2013, Cell. Signal. 25(5): 1301--1309
Drosophila miR-960 negatively regulates Hedgehog signaling by suppressing Smoothened, Costal-2 and Fused.
-
Dejima et al., 2013, J. Biol. Chem. 288(48): 34384--34393
Analysis of Drosophila Glucuronyl C5-Epimerase: IMPLICATIONS FOR DEVELOPMENTAL ROLES OF HEPARAN SULFATE SULFATION COMPENSATION AND 2-O-SULFATED GLUCURONIC ACID.
-
Sidor et al., 2013, Curr. Biol. 23(3): 223--228
Mask Proteins Are Cofactors of Yorkie/YAP in the Hippo Pathway.
-
Taliaferro et al., 2013, PLoS ONE 8(2): e56401
The Drosophila Splicing Factor PSI Is Phosphorylated by Casein Kinase II and Tousled-Like Kinase.
-
Petrova et al., 2013, Mol. Cell. Biol. 33(20): 4116--4127
Homodimerization of the Wnt Receptor DERAILED Recruits the Src Family Kinase SRC64B.
-
Baumgartner et al., 2013, PLoS Genet. 9(7): e1003598
The RNA-binding Proteins FMR1, Rasputin and Caprin Act Together with the UBA Protein Lingerer to Restrict Tissue Growth in Drosophila melanogaster.
-
Lim et al., 2013, Genes Cells 18(11): 909--920
Ebi alleviates excessive growth signaling through multiple epigenetic functions in Drosophila.
-
Guo et al., 2013, Cell Res. 23(10): 1201--1214
A novel partner of Scalloped regulates Hippo signaling via antagonizing Scalloped-Yorkie activity.
-
Smith et al., 2013, Genetics 195(1): 127--146
Maintenance of interphase chromosome compaction and homolog pairing in Drosophila is regulated by the condensin cap-h2 and its partner mrg15.
-
Kearse et al., 2013, Nucleus 4(3): 241--258
RpL22e, but not RpL22e-like-PA, is SUMOylated and localizes to the nucleoplasm of Drosophila meiotic spermatocytes.
-
German et al., 2013, Insect Biochem. Mol. Biol. 43(2): 138--145
Insights into subunit interactions within the insect olfactory receptor complex using FRET.
-
Pankotai et al., 2013, BMC Genomics 14: 44
Functional characterization and gene expression profiling of Drosophila melanogaster short dADA2b isoform-containing dSAGA complexes.
-
Yu et al., 2013, Development 140(17): 3635--3644
CAF-1 promotes Notch signaling through epigenetic control of target gene expression during Drosophila development.
-
Barišić-Jäger et al., 2013, PLoS ONE 8(8): e71860
HPat a Decapping Activator Interacting with the miRNA Effector Complex.
-
Jin et al., 2013, eLife 2: e00999
Brahma is essential for Drosophila intestinal stem cell proliferation and regulated by Hippo signaling.
-
Magny et al., 2013, Science 341(6150): 1116--1120
Conserved regulation of cardiac calcium uptake by peptides encoded in small open reading frames.
-
Ong et al., 2013, Cell 155(1): 148--159
Poly(ADP-ribosyl)ation Regulates Insulator Function and Intrachromosomal Interactions in Drosophila.
-
Nagy et al., 2013, PLoS Genet. 9(8): e1003664
Myc-Driven Overgrowth Requires Unfolded Protein Response-Mediated Induction of Autophagy and Antioxidant Responses in Drosophila melanogaster.
-
Havula et al., 2013, PLoS Genet. 9(4): e1003438
Mondo/ChREBP-Mlx-Regulated Transcriptional Network Is Essential for Dietary Sugar Tolerance in Drosophila.
-
Yeh and Bratton, 2013, Proc. Natl. Acad. Sci. U.S.A. 110(35): 14284--14289
Caspase-dependent regulation of the ubiquitin-proteasome system through direct substrate targeting.
-
Weng et al., 2013, eLife 2: e00640
miR-124 controls male reproductive success in Drosophila.
-
Kaasik et al., 2013, Cell Metab. 17(2): 291--302
Glucose Sensor O-GlcNAcylation Coordinates with Phosphorylation to Regulate Circadian Clock.
-
Cugusi et al., 2013, Transcription 4(5): 238--250
Topoisomerase II plays a role in dosage compensation in Drosophila.
-
Nishida et al., 2013, Mol. Cell 49(4): 680--691
Roles of R2D2, a Cytoplasmic D2 Body Component, in the Endogenous siRNA Pathway in Drosophila.
-
Yagi et al., 2013, Genes Cells 18(11): 934--945
fat facets induces polyubiquitination of Imd and inhibits the innate immune response in Drosophila.
-
Xiong et al., 2013, Proc. Natl. Acad. Sci. U.S.A. 110(41): 16520--16525
Core small nuclear ribonucleoprotein particle splicing factor SmD1 modulates RNA interference in Drosophila.
-
Sansores-Garcia et al., 2013, Curr. Biol. 23(3): 229--235
Mask Is Required for the Activity of the Hippo Pathway Effector Yki/YAP.
-
Al-Jubran et al., 2013, RNA 19(12): 1669--1683
Visualization of the joining of ribosomal subunits reveals the presence of 80S ribosomes in the nucleus.
-
Huntzinger et al., 2013, Nucleic Acids Res. 41(2): 978--994
The interactions of GW182 proteins with PABP and deadenylases are required for both translational repression and degradation of miRNA targets.
-
Reddy and Irvine, 2013, Dev. Cell 24(5): 459--471
Regulation of Hippo Signaling by EGFR-MAPK Signaling through Ajuba Family Proteins.
-
Olson et al., 2013, eLife 2: e00542
The insulin receptor cellular IRES confers resistance to eIF4A inhibition.
-
Rahman et al., 2013, Aging Cell 12(4): 554--562
Declining signal dependence of Nrf2-MafS-regulated gene expression correlates with aging phenotypes.
-
Kaipa et al., 2013, J. Cell Sci. 126(1): 360--372
Dock mediates Scar- and WASp-dependent actin polymerization through interaction with cell adhesion molecules in founder cells and fusion-competent myoblasts.
-
Stelter et al., 2013, Biol. Chem. 394(8): 1091--1096
High level expression of the Drosophila Toll receptor ectodomain and crystallization of its complex with the morphogen Spätzle.
-
Ramel et al., 2013, Nat. Cell Biol. 15(3): 317--324
Rab11 regulates cell-cell communication during collective cell movements.
-
Lu et al., 2013, Science 340(6128): 78--81
Drosophila H1 regulates the genetic activity of heterochromatin by recruitment of Su(var)3-9.
-
Xu et al., 2013, Nat. Neurosci. 16(9): 1238--1247
Top3β is an RNA topoisomerase that works with fragile X syndrome protein to promote synapse formation.
-
Da Ros et al., 2013, PLoS Biol. 11(5): e1001554
Dampening the Signals Transduced through Hedgehog via MicroRNA miR-7 Facilitates Notch-Induced Tumourigenesis.
-
Jauffred et al., 2013, Development 140(13): 2657--2668
Regulation of centrosome movements by Numb and the Collapsin Response Mediator Protein during Drosophila sensory progenitor asymmetric division.
-
Bawankar et al., 2013, RNA Biol. 10(2): 228--244
NOT10 and C2orf29/NOT11 form a conserved module of the CCR4-NOT complex that docks onto the NOT1 N-terminal domain.
-
Natalizio and Matera, 2013, Mol. Biol. Cell 24(18): 2932--2942
Identification and characterization of Drosophila Snurportin reveals a role for the import receptor Moleskin/importin-7 in snRNP biogenesis.
-
Liu et al., 2013, J. Cell Sci. 126(22): 5210--5223
Drosophila importin-7 functions upstream of the Elmo signaling module to mediate the formation and stability of muscle attachments.
-
Ilik et al., 2013, Mol. Cell 51(2): 156--173
Tandem Stem-Loops in roX RNAs Act Together to Mediate X Chromosome Dosage Compensation in Drosophila.
-
Wong et al., 2013, PLoS Biol. 11(9): e1001657
A Cullin1-Based SCF E3 Ubiquitin Ligase Targets the InR/PI3K/TOR Pathway to Regulate Neuronal Pruning.
-
Lee et al., 2013, Neuron 78(5): 813--826
Interactions between a Receptor Tyrosine Phosphatase and a Cell Surface Ligand Regulate Axon Guidance and Glial-Neuronal Communication.
-
Li et al., 2013, PLoS ONE 8(3): e58301
Mei-p26 cooperates with bam, bgcn and sxl to promote early germline development in the Drosophila ovary.
-
Huang et al., 2013, PLoS Biol. 11(11): e1001721
Activation of Smurf E3 ligase promoted by smoothened regulates hedgehog signaling through targeting patched turnover.
-
Wang et al., 2013, J. Cell Biol. 202(2): 277--293
Cell cycle regulation of Greatwall kinase nuclear localization facilitates mitotic progression.
-
Strutt et al., 2013, Development 140(8): 1693--1702
A Cul-3-BTB ubiquitylation pathway regulates junctional levels and asymmetry of core planar polarity proteins.
-
Burnette et al., 2014, Mol. Biosyst. 10(10): 2713--2723
An inverse small molecule screen to design a chemically defined medium supporting long-term growth of Drosophila cell lines.
-
Vogelmann et al., 2014, PLoS Genet. 10(8): e1004544
Chromatin insulator factors involved in long-range DNA interactions and their role in the folding of the Drosophila genome.
-
Gagliardi et al., 2014, J. Cell Sci. 127(22): 4918--4926
Inhibitors of endocytosis prevent Wnt/Wingless signalling by reducing the level of basal β-catenin/Armadillo.
-
Hassel et al., 2014, Development 141(1): 112--123
Induction of endocycles represses apoptosis independently of differentiation and predisposes cells to genome instability.
-
Wang and Page-McCaw, 2014, J. Cell Biol. 206(7): 923--936
A matrix metalloproteinase mediates long-distance attenuation of stem cell proliferation.
-
Bi et al., 2014, Cell Metab. 19(5): 861--871
Seipin Promotes Adipose Tissue Fat Storage through the ER Ca(2+)-ATPase SERCA.
-
Bonnay et al., 2014, EMBO J. 33(20): 2349--2362
Akirin specifies NF-κB selectivity of Drosophila innate immune response via chromatin remodeling.
-
Kunduri et al., 2014, J. Cell Biol. 206(1): 79--95
Phosphatidic acid phospholipase A1 mediates ER-Golgi transit of a family of G protein-coupled receptors.
-
Weidmann et al., 2014, RNA 20(8): 1298--1319
The RNA binding domain of Pumilio antagonizes poly-adenosine binding protein and accelerates deadenylation.
-
Praveen et al., 2014, PLoS Genet. 10(8): e1004489
SMA-Causing Missense Mutations in Survival motor neuron (Smn) Display a Wide Range of Phenotypes When Modeled in Drosophila.
-
Pan et al., 2014, Nature 514(7521): 233--236
Protein competition switches the function of COP9 from self-renewal to differentiation.
-
Bade et al., 2014, Dev. Cell 28(5): 508--519
The E3 Ligase CUL3/RDX Controls Centromere Maintenance by Ubiquitylating and Stabilizing CENP-A in a CAL1-Dependent Manner.
-
Liang et al., 2014, Mol. Cell 53(4): 672--681
Chromatin Immunoprecipitation Indirect Peaks Highlight Long-Range Interactions of Insulator Proteins and Pol II Pausing.
-
Liu et al., 2014, Cell Res. 24(5): 595--609
Hedgehog signaling downregulates Suppressor of Fused through the HIB/SPOP-Crn axis in Drosophila.
-
Li et al., 2014, Dev. Cell 31(3): 291--304
The conserved misshapen-warts-yorkie pathway acts in enteroblasts to regulate intestinal stem cells in Drosophila.
-
Sechi et al., 2014, PLoS Genet. 10(5): e1004305
GOLPH3 Is Essential for Contractile Ring Formation and Rab11 Localization to the Cleavage Site during Cytokinesis in Drosophila melanogaster.
-
Seo et al., 2014, Biochem. Biophys. Res. Commun. 451(4): 644--649
Cellular inhibitor of apoptosis protein 1 ubiquitinates endonuclease G but does not affect endonuclease G-mediated cell death.
-
Sudhakaran et al., 2014, Proc. Natl. Acad. Sci. U.S.A. 111(1): E99--EE108
FMRP and Ataxin-2 function together in long-term olfactory habituation and neuronal translational control.
-
Vuong et al., 2014, Development 141(16): 3222--3232
Kinesin-II recruits Armadillo and Dishevelled for Wingless signaling in Drosophila.
-
Chen et al., 2014, Dev. Cell 30(5): 569--584
Ena/VASP Proteins Cooperate with the WAVE Complex to Regulate the Actin Cytoskeleton.
-
Zhang et al., 2014, Science 343(6168): 298--301
Changes in rRNA transcription influence proliferation and cell fate within a stem cell lineage.
-
Patil et al., 2014, BMC Biol. 12(1): 61
The Tudor domain protein Tapas, a homolog of the vertebrate Tdrd7, functions in the piRNA pathway to regulate retrotransposons in germline of Drosophila melanogaster.
-
Ghosh et al., 2014, PLoS Genet. 10(6): e1004455
The EJC Binding and Dissociating Activity of PYM Is Regulated in Drosophila.
-
Militti et al., 2014, Nat. Commun. 5: 4762
UNR facilitates the interaction of MLE with the lncRNA roX2 during Drosophila dosage compensation.
-
Lim et al., 2014, RNA Biol. 11(9): 1171--1179
Requirement for CRIF1 in RNA interference and Dicer-2 stability.
-
Sakuma et al., 2014, Nat. Commun. 5: 5180
Drosophila Strip serves as a platform for early endosome organization during axon elongation.
-
Nagy et al., 2014, Autophagy 10(3): 453--467
Atg17/FIP200 localizes to perilysosomal Ref(2)P aggregates and promotes autophagy by activation of Atg1 in Drosophila.
-
Sahashi et al., 2014, J. Cell Sci. 127(14): 3066--3078
DNA polymerase α interacts with PrSet7 and mediates H4K20 monomethylation in Drosophila.
-
Avet-Rochex et al., 2014, PLoS Genet. 10(9): e1004624
Unkempt Is Negatively Regulated by mTOR and Uncouples Neuronal Differentiation from Growth Control.
-
Bulat et al., 2014, J. Cell Biol. 204(1): 77--94
Presynaptic CK2 promotes synapse organization and stability by targeting Ankyrin2.
-
Mao et al., 2014, J. Biol. Chem. 289(32): 22333--22341
The Kto-Skd Complex Can Regulate ptc Expression by Interacting with Cubitus interruptus (Ci) in the Hedgehog Signaling Pathway.
-
White-Grindley et al., 2014, PLoS Biol. 12(2): e1001786
Contribution of Orb2A Stability in Regulated Amyloid-Like Oligomerization of Drosophila Orb2.
-
Hsiao et al., 2014, J. Cell Sci. 127(1): 182--190
Proneural proteins Achaete and Scute associate with nuclear actin to promote formation of external sensory organs.
-
Wallace et al., 2014, Development 141(6): 1332--1341
TRIP/NOPO E3 ubiquitin ligase promotes ubiquitylation of DNA polymerase η.
-
Xie et al., 2014, J. Cell Sci. 127(17): 3830--3839
E(y)1/TAF9 mediates the transcriptional output of Notch signaling in Drosophila.
-
Gillingham et al., 2014, Dev. Cell 31(3): 358--373
Toward a comprehensive map of the effectors of rab GTPases.
-
Ji et al., 2014, Nat. Commun. 5: 3458
Cell-surface localization of Pellino antagonizes Toll-mediated innate immune signalling by controlling MyD88 turnover in Drosophila.
-
Benbahouche et al., 2014, J. Biol. Chem. 289(9): 6236--6247
Drosophila Spag Is the Homolog of RNA Polymerase II-associated Protein 3 (RPAP3) and Recruits the Heat Shock Proteins 70 and 90 (Hsp70 and Hsp90) during the Assembly of Cellular Machineries.
-
Thomas and Strutt, 2014, Dev. Biol. 385(1): 107--121
Rabaptin-5 and Rabex-5 are neoplastic tumour suppressor genes that interact to modulate Rab5 dynamics in Drosophila melanogaster.
-
Rowshanravan et al., 2014, J. Cell Sci. 127(13): 2849--2861
RasGAP mediates neuronal survival in Drosophila through direct regulation of Rab5-dependent endocytosis.
-
Yang et al., 2014, Cell Death Differ. 21(4): 604--611
The deubiquitinating enzyme DUBAI stabilizes DIAP1 to suppress Drosophila apoptosis.
-
Ryu et al., 2014, J. Proteomics 102: 137--147
Analysis of the heterochromatin protein 1 (HP1) interactome in Drosophila.
-
Wang et al., 2014, Dev. Biol. 394(1): 156--169
The proteins encoded by the Drosophila Planar Polarity Effector genes inturned, fuzzy and fritz interact physically and can re-pattern the accumulation of "upstream" Planar Cell Polarity proteins.
-
Ashton-Beaucage et al., 2014, PLoS Biol. 12(3): e1001809
A Functional Screen Reveals an Extensive Layer of Transcriptional and Splicing Control Underlying RAS/MAPK Signaling in Drosophila.
-
Goto et al., 2014, J. Biol. Chem. 289(30): 20470--20476
The Chromatin Regulator DMAP1 Modulates Activity of the Nuclear Factor κB (NF-κB) Transcription Factor Relish in the Drosophila Innate Immune Response.
-
Künnapuu et al., 2014, Dev. Biol. 389(2): 149--159
Cleavage of the Drosophila screw prodomain is critical for a dynamic BMP morphogen gradient in embryogenesis.
-
Yatsenko and Shcherbata, 2014, Dev. Cell 28(3): 335--348
Drosophila miR-9a Targets the ECM Receptor Dystroglycan to Canalize Myotendinous Junction Formation.
-
Belozerov et al., 2014, Mol. Cell. Biol. 34(3): 474--484
In Vivo Interaction Proteomics Reveal a Novel p38 Mitogen-Activated Protein Kinase/Rack1 Pathway Regulating Proteostasis in Drosophila Muscle.
-
Wei and Lilly, 2014, Cell Death Differ. 21(9): 1460--1468
The TORC1 inhibitors Nprl2 and Nprl3 mediate an adaptive response to amino-acid starvation in Drosophila.
-
Cuartero et al., 2014, EMBO J. 33(6): 637--647
Ibf1 and Ibf2 are novel CP190-interacting proteins required for insulator function.
-
Barrio et al., 2014, Cell Rep. 8(2): 528--541
MicroRNA-Mediated Regulation of Dp53 in the Drosophila Fat Body Contributes to Metabolic Adaptation to Nutrient Deprivation.
-
Huang et al., 2014, Cell Death Differ. 21(12): 1961--1970
Ubr3 E3 ligase regulates apoptosis by controlling the activity of DIAP1 in Drosophila.
-
Charng et al., 2014, PLoS Biol. 12(1): e1001777
Drosophila Tempura, a Novel Protein Prenyltransferase α Subunit, Regulates Notch Signaling Via Rab1 and Rab11.
-
Mohan et al., 2014, Genes Dev. 28(3): 259--272
Loss of Drosophila Ataxin-7, a SAGA subunit, reduces H2B ubiquitination and leads to neural and retinal degeneration.
-
Engel et al., 2014, Cell Commun. Signal. 12(1): 41
Identifying USPs regulating immune signals in Drosophila: USP2 deubiquitinates Imd and promotes its degradation by interacting with the proteasome.
-
Takáts et al., 2014, Mol. Biol. Cell 25(8): 1338--1354
Interaction of the HOPS complex with Syntaxin 17 mediates autophagosome clearance in Drosophila.
-
Boube et al., 2014, PLoS Genet. 10(5): e1004303
Drosophila melanogaster Hox Transcription Factors Access the RNA Polymerase II Machinery through Direct Homeodomain Binding to a Conserved Motif of Mediator Subunit Med19.
-
Tutor et al., 2014, Development 141(2): 367--376
Src64B phosphorylates Dumbfounded and regulates slit diaphragm dynamics: Drosophila as a model to study nephropathies.
-
Rošić et al., 2014, J. Cell Biol. 207(3): 335--349
Repetitive centromeric satellite RNA is essential for kinetochore formation and cell division.
-
Morelli et al., 2014, Autophagy 10(12): 2251--2268
Multiple functions of the SNARE protein Snap29 in autophagy, endocytic, and exocytic trafficking during epithelial formation in Drosophila.
-
Claudius et al., 2014, PLoS Genet. 10(4): e1004287
Unexpected Role of the Steroid-Deficiency Protein Ecdysoneless in Pre-mRNA Splicing.
-
Mauri et al., 2014, Curr. Biol. 24(16): 1811--1825
The Conserved Discs-large Binding Partner Banderuola Regulates Asymmetric Cell Division in Drosophila.
-
Koe et al., 2014, eLife 3: e01906
The Brm-HDAC3-Erm repressor complex suppresses dedifferentiation in Drosophila type II neuroblast lineages.
-
Aerne et al., 2015, PLoS ONE 10(6): e0131113
Hippo Stabilises Its Adaptor Salvador by Antagonising the HECT Ubiquitin Ligase Herc4.
-
Kim and Lee, 2015, Int. J. Mol. Sci. 16(4): 7015--7026
Identification of an AMPK Phosphorylation Site in Drosophila TSC2 (gigas) that Regulate Cell Growth.
-
Kakugawa et al., 2015, Nature 519(7542): 187--192
Notum deacylates Wnt proteins to suppress signalling activity.
-
Luo et al., 2015, J. Cell Biol. 209(4): 595--608
Wnt ligands regulate Tkv expression to constrain Dpp activity in the Drosophila ovarian stem cell niche.
-
Powell and Dion, 2015, J. Mol. Evol. 80(3-4): 219--226
Effects of codon usage on gene expression: empirical studies on Drosophila.
-
Liu et al., 2015, Proc. Natl. Acad. Sci. U.S.A. 112(15): E1871--E1879
Juvenile hormone-activated phospholipase C pathway enhances transcriptional activation by the methoprene-tolerant protein.
-
de Madrid et al., 2015, Dev. Biol. 399(2): 283--295
RhoGAP68F controls transport of adhesion proteins in Rab4 endosomes to modulate epithelial morphogenesis of Drosophila leg discs.
-
Crona et al., 2015, Dev. Biol. 407(1): 173--181
The Brakeless co-regulator can directly activate and repress transcription in early Drosophila embryos.
-
Ray et al., 2015, Dev. Cell 34(3): 310--322
Patterned Anchorage to the Apical Extracellular Matrix Defines Tissue Shape in the Developing Appendages of Drosophila.
-
Kiparaki et al., 2015, Nucleic Acids Res. 43(5): 2543--2559
bHLH proteins involved in Drosophila neurogenesis are mutually regulated at the level of stability.
-
Trogden and Rogers, 2015, PLoS ONE 10(9): e0138966
TOG Proteins Are Spatially Regulated by Rac-GSK3β to Control Interphase Microtubule Dynamics.
-
Fletcher et al., 2015, EMBO J. 34(7): 940--954
The Spectrin cytoskeleton regulates the Hippo signalling pathway.
-
Auer et al., 2015, Cell. Signal. 27(1): 115--124
MAPK-dependent phosphorylation modulates the activity of Suppressor of Hairless in Drosophila.
-
Liu et al., 2015, G3 (Bethesda) 6(1): 121--132
Disruption of Methionine Metabolism in Drosophila melanogaster Impacts Histone Methylation and Results in Loss of Viability.
-
Perrin et al., 2015, J. Innate Immun. 7(1): 37--46
The Nonaspanins TM9SF2 and TM9SF4 Regulate the Plasma Membrane Localization and Signalling Activity of the Peptidoglycan Recognition Protein PGRP-LC in Drosophila.
-
Zhang et al., 2015, Cell Res. 25(1): 93--109
SCF(Slmb) E3 ligase-mediated degradation of Expanded is inhibited by the Hippo pathway in Drosophila.
-
Yuva-Aydemir et al., 2015, PLoS Genet. 11(5): e1005264
Downregulation of the Host Gene jigr1 by miR-92 Is Essential for Neuroblast Self-Renewal in Drosophila.
-
Eberle et al., 2015, PLoS Genet. 11(9): e1005523
An Interaction between RRP6 and SU(VAR)3-9 Targets RRP6 to Heterochromatin and Contributes to Heterochromatin Maintenance in Drosophila melanogaster.
-
Di Cara et al., 2015, Cell Death Differ. 22(9): 1526--1539
The Hippo pathway promotes cell survival in response to chemical stress.
-
Baker et al., 2015, Development 142(19): 3394--3402
Cell type-specific translational repression of Cyclin B during meiosis in males.
-
Barrios et al., 2015, PLoS Genet. 11(8): e1005463
The Homeodomain Iroquois Proteins Control Cell Cycle Progression and Regulate the Size of Developmental Fields.
-
Maksimenko et al., 2015, Genome Res. 25(1): 89--99
Two new insulator proteins, Pita and ZIPIC, target CP190 to chromatin.
-
Zhao et al., 2015, PLoS Genet. 11(3): e1004984
Drosophila S6 Kinase Like Inhibits Neuromuscular Junction Growth by Downregulating the BMP Receptor Thickveins.
-
Dupont et al., 2015, Epigenetics Chromatin 8: 18
Drosophila Cyclin G and epigenetic maintenance of gene expression during development.
-
Dong et al., 2015, J. Mol. Cell. Biol. 7(5): 415--428
Growth suppressor lingerer regulates bantam microRNA to restrict organ size.
-
Lee et al., 2015, Development 142(1): 162--173
Coordinate control of terminal dendrite patterning and dynamics by the membrane protein Raw.
-
Eikenes et al., 2015, PLoS Genet. 11(1): e1004904
ALIX and ESCRT-III Coordinately Control Cytokinetic Abscission during Germline Stem Cell Division In Vivo.
-
Yan and Perrimon, 2015, Proc. Natl. Acad. Sci. U.S.A. 112(37): 11606--11611
spenito is required for sex determination in Drosophila melanogaster.
-
Rosa et al., 2015, Dev. Cell 32(5): 604--616
Ect2/Pbl acts via Rho and polarity proteins to direct the assembly of an isotropic actomyosin cortex upon mitotic entry.
-
Shanshan and Laixin, 2015, Yi Chuan 37(11): 1160--1166
Identification of C(2)M interacting proteins by yeast two-hybrid screening.
-
Cenci et al., 2015, PLoS Genet. 11(6): e1005260
The Analysis of Pendolino (peo) Mutants Reveals Differences in the Fusigenic Potential among Drosophila Telomeres.
-
Lipinszki et al., 2015, Nat. Commun. 6: 5894
Centromeric binding and activity of Protein Phosphatase 4.
-
Kimura et al., 2015, J. Neurogenet. 29(1): 8--17
The Drosophila lingerer protein cooperates with Orb2 in long-term memory formation.
-
Laflamme and Emery, 2015, Methods Mol. Biol. 1298: 187--194
In Vitro and In Vivo Characterization of the Rab11-GAP Activity of Drosophila Evi5.
-
Marin-Vicente et al., 2015, J. Cell Sci. 128(6): 1097--1107
RRP6/EXOSC10 is required for the repair of DNA double-strand breaks by homologous recombination.
-
Fehler et al., 2015, Nucleic Acids Res. 42(17): 11107--11118
An evolutionarily conserved interaction of tumor suppressor protein Pdcd4 with the poly(A)-binding protein contributes to translation suppression by Pdcd4.
-
Moncrieff et al., 2015, PLoS ONE 10(9): e0136760
Regulation of hedgehog Ligand Expression by the N-End Rule Ubiquitin-Protein Ligase Hyperplastic Discs and the Drosophila GSK3β Homologue, Shaggy.
-
Klebba et al., 2015, J. Cell Biol. 208(4): 401--414
Two Polo-like kinase 4 binding domains in Asterless perform distinct roles in regulating kinase stability.
-
Sun et al., 2015, Nat. Commun. 6: 8402
Localization of Hippo signalling complexes and Warts activation in vivo.
-
Ren et al., 2015, PLoS Genet. 11(4): e1005180
Windpipe Controls Drosophila Intestinal Homeostasis by Regulating JAK/STAT Pathway via Promoting Receptor Endocytosis and Lysosomal Degradation.
-
Shen et al., 2015, Cell Res. 25: 997--1012
A miR-130a-YAP positive feedback loop promotes organ size and tumorigenesis.
-
Wen et al., 2015, Mol. Cell 57(1): 165--178
Adaptive regulation of testis gene expression and control of male fertility by the Drosophila harpin RNA pathway.
-
Dent et al., 2015, Curr. Biol. 25(1): 124--130
The GTPase Regulatory Proteins Pix and Git Control Tissue Growth via the Hippo Pathway.
-
Li et al., 2015, Cell Res. 25(10): 1152--1170
Ci antagonizes Hippo signaling in the somatic cells of the ovary to drive germline stem cell differentiation.
-
Wang et al., 2015, Nat. Commun. 6: 6607
Suppressor of Deltex mediates Pez degradation and modulates Drosophila midgut homeostasis.
-
Reynaud et al., 2015, Cell Rep. 11(8): 1293--1304
Guidance of Drosophila Mushroom Body Axons Depends upon DRL-Wnt Receptor Cleavage in the Brain Dorsomedial Lineage Precursors.
-
Zaessinger et al., 2015, Development 142(6): 1102--1112
Drosophila MAGI interacts with RASSF8 to regulate E-Cadherin-based adherens junctions in the developing eye.
-
Akhmetova et al., 2015, Mol. Biol. Cell 26(1): 15--28
Functional insight into the role of Orc6 in septin complex filament formation in Drosophila.
-
Suh et al., 2015, Nat. Commun. 6: 7693
Genome-wide microRNA screening reveals that the evolutionary conserved miR-9a regulates body growth by targeting sNPFR1/NPYR.
-
Li and Dijkers, 2015, J. Immunol. 194(1): 168--176
Specific calcineurin isoforms are involved in Drosophila toll immune signaling.
-
Andreazza et al., 2015, Cell Rep. 11(8): 1266--1279
Daytime CLOCK Dephosphorylation Is Controlled by STRIPAK Complexes in Drosophila.
-
Dascenco et al., 2015, Cell 162(5): 1140--1154
Slit and Receptor Tyrosine Phosphatase 69D Confer Spatial Specificity to Axon Branching via Dscam1.
-
Tiebe et al., 2015, Dev. Cell 33(3): 272--284
REPTOR and REPTOR-BP Regulate Organismal Metabolism and Transcription Downstream of TORC1.
-
Sterne et al., 2015, eLife 4: e05196
Dysregulated Dscam levels act through Abelson tyrosine kinase to enlarge presynaptic arbors.
-
Lovato et al., 2015, PLoS ONE 10(7): e0132965
The Drosophila Transcription Factors Tinman and Pannier Activate and Collaborate with Myocyte Enhancer Factor-2 to Promote Heart Cell Fate.
-
Girdler et al., 2016, J. Cell Sci. 129(1): 121--134
The Gas2 family protein Pigs is a microtubule +TIP that affects cytoskeleton organisation.
-
Saha et al., 2016, BMC Genomics 17(1): 111
Genome-wide studies reveal novel and distinct biological pathways regulated by SIN3 isoforms.
-
Chaubal et al., 2016, J. Biol. Chem. 291(22): 11566--11571
Inter-isoform-dependent Regulation of the Drosophila Master Transcriptional Regulator SIN3.
-
Sanfilippo et al., 2016, Development 143(23): 4474--4485
Neural specificity of the RNA-binding protein Elav is achieved by post-transcriptional repression in non-neural tissues.
-
Gajan et al., 2016, Epigenetics Chromatin 9: 4
The histone demethylase dKDM5/LID interacts with the SIN3 histone deacetylase complex and shares functional similarities with SIN3.
-
Raisch et al., 2016, EMBO J. 35(9): 974--990
Distinct modes of recruitment of the CCR4-NOT complex by Drosophila and vertebrate Nanos.
-
Aram et al., 2016, Dev. Cell 37(1): 15--33
A Krebs Cycle Component Limits Caspase Activation Rate through Mitochondrial Surface Restriction of CRL Activation.
-
Peng et al., 2016, Nat. Genet. 48(3): 283--291
Piwi maintains germline stem cells and oogenesis in Drosophila through negative regulation of Polycomb group proteins.
-
Jiang et al., 2016, J. Genet. Genomics 43(1): 11--24
Drosophila Homolog of FMRP Maintains Genome Integrity by Interacting with Piwi.
-
Ma et al., 2016, Oncogene 35(7): 846--855
Rho1-Wnd signaling regulates loss-of-cell polarity-induced cell invasion in Drosophila.
-
Hur et al., 2016, Genes Dev. 30(7): 840--855
Splicing-independent loading of TREX on nascent RNA is required for efficient expression of dual-strand piRNA clusters in Drosophila.
-
Hu et al., 2016, Cell Discov. 2: 15047
Ack promotes tissue growth via phosphorylation and suppression of the Hippo pathway component Expanded.
-
Zhang et al., 2016, Sci. Rep. 6: 22348
dFoxO promotes Wingless signaling in Drosophila.
-
Kopytova et al., 2016, Nucleic Acids Res. 44(10): 4920--4933
ORC interacts with THSC/TREX-2 and its subunits promote Nxf1 association with mRNP and mRNA export in Drosophila.
-
Wu et al., 2016, Proc. Natl. Acad. Sci. U.S.A. 113(15): 4134--4139
Major spliceosome defects cause male infertility and are associated with nonobstructive azoospermia in humans.
-
Khoshnood et al., 2016, Cell. Molec. Life Sci. 73(9): 1939--1954
Urm1: an essential regulator of JNK signaling and oxidative stress in Drosophila melanogaster.
-
Orme et al., 2016, Nat. Commun. 7: 10972
The unconventional myosin CRINKLED and its mammalian orthologue MYO7A regulate caspases in their signalling roles.
-
Kuzuoğlu-Öztürk et al., 2016, EMBO J. 35(11): 1186--1203
miRISC and the CCR4-NOT complex silence mRNA targets independently of 43S ribosomal scanning.
-
Meltzer et al., 2016, Neuron 89(4): 741--755
Epidermis-Derived Semaphorin Promotes Dendrite Self-Avoidance by Regulating Dendrite-Substrate Adhesion in Drosophila Sensory Neurons.
-
Peng et al., 2016, J. Neurosci. 36(16): 4635--4646
cGMP-Dependent Protein Kinase Encoded by foraging Regulates Motor Axon Guidance in Drosophila by Suppressing Lola Function.
-
Top et al., 2016, Cell Rep. 16(2): 357--367
GSK-3 and CK2 Kinases Converge on Timeless to Regulate the Master Clock.
-
Suganuma et al., 2016, J. Mol. Cell. Biol. 8(1): 44--50
Moco biosynthesis and the ATAC acetyltransferase engage translation initiation by inhibiting latent PKR activity.
-
Olovnikov et al., 2016, Biochemistry, Moscow 81(9): 1023--1030
Interaction of Telomeric Retroelement HeT-A Transcripts and Their Protein Product Gag in Early Embryogenesis of Drosophila.
-
Richter et al., 2016, Open Biol. 6(2): 150238
Network of protein interactions within the Drosophila inner kinetochore.
-
Brewer-Jensen et al., 2016, RNA 22(1): 139--154
Suppressor of sable [Su(s)] and Wdr82 down-regulate RNA from heat-shock-inducible repetitive elements by a mechanism that involves transcription termination.
-
Lee et al., 2016, Proc. Natl. Acad. Sci. U.S.A. 113(33): E4904--E4913
Pacemaker-neuron-dependent disturbance of the molecular clockwork by a Drosophila CLOCK mutant homologous to the mouse Clock mutation.
-
Fu et al., 2016, Nat. Cell Biol. 18(1): 87--99
Conserved molecular interactions in centriole-to-centrosome conversion.
-
López-Panadès and Casacuberta, 2016, Insect Biochem. Mol. Biol. 70: 111--115
NAP-1, Nucleosome assembly protein 1, a histone chaperone involved in Drosophila telomeres.
-
Safi et al., 2016, Mol. Biol. Cell 27(6): 907--918
Drosophila Nedd4-long reduces Amphiphysin levels in muscles and leads to impaired T-tubule formation.
-
Ray et al., 2016, Proc. Natl. Acad. Sci. U.S.A. 113(14): 3826--3831
Combgap contributes to recruitment of Polycomb group proteins in Drosophila.
-
Ozawa et al., 2016, Genes Cells 21(5): 442--456
Organ identity specification factor WGE localizes to the histone locus body and regulates histone expression to ensure genomic stability in Drosophila.
-
Wang et al., 2016, J. Biol. Chem. 291(15): 7926--7937
Importin α1 Mediates Yorkie Nuclear Import via an N-terminal Non-canonical Nuclear Localization Signal.
-
Tan et al., 2016, Dev. Biol. 410(2): 202--212
Zfrp8 forms a complex with fragile-X mental retardation protein and regulates its localization and function.
-
Chen et al., 2016, J. Biol. Chem. 291(25): 13216--13228
The C-terminal 20 Amino Acids of Drosophila Topoisomerase 2 Are Required for Binding to a BRCA1 C Terminus (BRCT) Domain-containing Protein, Mus101, and Fidelity of DNA Segregation.
-
Galletta et al., 2016, J. Cell Biol. 213(4): 435--450
Asterless is required for centriole length control and sperm development.
-
Jin and Mardon, 2016, Sci. Rep. 6: 23228
Distinct Biochemical Activities of Eyes absent During Drosophila Eye Development.
-
Lee et al., 2016, PLoS Genet. 12(5): e1006043
Maintenance of Stem Cell Niche Integrity by a Novel Activator of Integrin Signaling.
-
Patel et al., 2016, Dev. Biol. 414(1): 100--107
Gia/Mthl5 is an aorta specific GPCR required for Drosophila heart tube morphology and normal pericardial cell positioning.
-
Hervás et al., 2016, PLoS Biol. 14(1): e1002361
Molecular Basis of Orb2 Amyloidogenesis and Blockade of Memory Consolidation.
-
Ji and Tulin, 2016, Mol. Cell. Biol. 36(19): 2476--2486
Poly(ADP-Ribosyl)ation of hnRNP A1 Protein Controls Translational Repression in Drosophila.
-
Tie et al., 2016, Proc. Natl. Acad. Sci. U.S.A. 113(6): E744--E753
Polycomb inhibits histone acetylation by CBP by binding directly to its catalytic domain.
-
Wang et al., 2016, Development 143(3): 530--539
Antagonistic roles of Nibbler and Hen1 in modulating piRNA 3' ends in Drosophila.
-
Squarr et al., 2016, J. Cell Biol. 212(5): 591--603
Fat2 acts through the WAVE regulatory complex to drive collective cell migration during tissue rotation.
-
Bairoch, 2016, The Cellosaurus: a cell line knowledge resource.
The Cellosaurus: a cell line knowledge resource.
-
Tapon, 2016.4.22, Cultured cell line used in Aerne et al. 2015.
Cultured cell line used in Aerne et al. 2015.
-
Cherbas, 2016.3.25, Origin and DGRC categorization of various S2 cell lines.
Origin and DGRC categorization of various S2 cell lines.
-
Garcia et al., 2016, RNA 22(8): 1215--1227
Transcriptomic comparison of Drosophila snRNP biogenesis mutants reveals mutant-specific changes in pre-mRNA processing: implications for spinal muscular atrophy.
-
Pérez-Moreno et al., 2017, J. Cell Sci. 130(5): 950--962
Kon-tiki enhances PS2 integrin adhesion and localizes its ligand, Thrombospondin, in the myotendinous junction.
-
Strom et al., 2017, Nature 547(7662): 241--245
Phase separation drives heterochromatin domain formation.
-
Luo et al., 2017, Development 144(18): 3224--3231
Engrailed acts with Nejire to control decapentaplegic expression in the Drosophila ovarian stem cell niche.
-
Martin et al., 2017, PLoS ONE 12(6): e0178590
A comparison of nucleosome organization in Drosophila cell lines.
-
Anderson and Wharton, 2017, J. Biol. Chem. 292(47): 19160--19178
Alternative cleavage of the bone morphogenetic protein (BMP), Gbb, produces ligands with distinct developmental functions and receptor preferences.
-
Pae et al., 2017, Dev. Cell 42(2): 130--142.e7
GCL and CUL3 Control the Switch between Cell Lineages by Mediating Localized Degradation of an RTK.
-
Neukomm et al., 2017, Neuron 95(1): 78--91.e5
Axon Death Pathways Converge on Axundead to Promote Functional and Structural Axon Disassembly.
-
Ramachandran et al., 2017, Mol. Cell 68(6): 1038--1053.e4
Transcription and Remodeling Produce Asymmetrically Unwrapped Nucleosomal Intermediates.
-
Hsia et al., 2017, Nat. Commun. 8(1): 1275
Hedgehog mediated degradation of Ihog adhesion proteins modulates cell segregation in Drosophila wing imaginal discs.
-
Berndt et al., 2017, eLife 6: e27346
Ubiquitylation-independent activation of Notch signalling by Delta.
-
Moura et al., 2017, eLife 6: e25366
Protein Phosphatase 1 inactivates Mps1 to ensure efficient Spindle Assembly Checkpoint silencing.
-
Cherbas et al., 2017.4.19, S2R+ and S2-DGRC cell lines used.
S2R+ and S2-DGRC cell lines used.
-
Shan et al., 2018, Nat. Commun. 9(1): 737
Basal condensation of Numb and Pon complex via phase transition during Drosophila neuroblast asymmetric division.
-
Gray et al., 2018, Mol. Biol. Cell 29(2): 96--110
Self-oligomerization regulates stability of survival motor neuron protein isoforms by sequestering an SCFSlmb degron.
-
Henriques et al., 2018, Genes Dev. 32(1): 26--41
Widespread transcriptional pausing and elongation control at enhancers.
-
Xu et al., 2018, eLife 7: e33934
Temporospatial induction of homeodomain gene cut dictates natural lineage reprogramming.
-
Martin et al., 2018, Cell Rep. 23(12): 3537--3550.e6
Analysis of Drosophila STING Reveals an Evolutionarily Conserved Antimicrobial Function.
-
Li and Baker, 2018, eLife 7: e33967
Regulation of the Drosophila ID protein Extra macrochaetae by proneural dimerization partners.
-
Li et al., 2018, Dev. Cell 45(4): 433--449.e6
Ingestion of Food Particles Regulates the Mechanosensing Misshapen-Yorkie Pathway in Drosophila Intestinal Growth.
-
Adikes et al., 2018, J. Cell Biol. 217(2): 779--793
Control of microtubule dynamics using an optogenetic microtubule plus end-F-actin cross-linker.
-
Yashiro et al., 2018, Cell Rep. 23(12): 3647--3657
Piwi Nuclear Localization and Its Regulatory Mechanism in Drosophila Ovarian Somatic Cells.
-
Kale et al., 2018, Dev. Cell 44(1): 42--55.e4
Ribosomal Protein S12e Has a Distinct Function in Cell Competition.
-
Baena-Lopez et al., 2018, Development 145(23): dev170811
Novel initiator caspase reporters uncover previously unknown features of caspase-activating cells.
-
Munden et al., 2018, eLife 7: e39140
Rif1 inhibits replication fork progression and controls DNA copy number in Drosophila.
-
Pellacani et al., 2018, eLife 7: e40325
Splicing factors Sf3A2 and Prp31 have direct roles in mitotic chromosome segregation.
-
Blazquez et al., 2018, Mol. Cell 72(3): 496--509.e9
Exon Junction Complex Shapes the Transcriptome by Repressing Recursive Splicing.
-
Yan et al., 2018, Cell Rep. 25(4): 1051--1065.e6
Microtubule Acetylation Is Required for Mechanosensation in Drosophila.
-
Cara et al., 2018, Mol. Biol. Cell 29(22): 2766--2783
Dysfunctional peroxisomes compromise gut structure and host defense by increased cell death and Tor-dependent autophagy.
-
Mahato et al., 2018, Dev. Biol. 443(2): 188--202
A mosaic of independent innovations involving eyes shut are critical for the evolutionary transition from fused to open rhabdoms.
-
Blanchette, 2018.2.9, Origin of S2 cells in FBrf0235552.
Origin of S2 cells in FBrf0235552.
-
Osswald et al., 2019, Biomolecules 9(2): E61
Light-Induced Protein Clustering for Optogenetic Interference and Protein Interaction Analysis in Drosophila S2 Cells.
-
Jouette et al., 2019, eLife 8: e40212
Dynein-mediated transport and membrane trafficking control PAR3 polarised distribution.
-
Wu et al., 2019, J. Biol. Chem. 294(33): 12339--12348
The Drosophila Hedgehog receptor component Interference hedgehog (Ihog) mediates cell-cell interactions through trans-homophilic binding.
-
Yu et al., 2019, Cell Death Dis. 10(4): 294
Srlp is crucial for the self-renewal and differentiation of germline stem cells via RpL6 signals in Drosophila testes.
-
Cheng et al., 2019, eLife 8: e41028
Molecular basis of synaptic specificity by immunoglobulin superfamily receptors in Drosophila.
-
Ahlers et al., 2019, Cell Rep. 29(7): 1946--1960.e5
Insulin Potentiates JAK/STAT Signaling to Broadly Inhibit Flavivirus Replication in Insect Vectors.
-
Petri et al., 2019, Cell Rep. 26(6): 1641--1653.e4
Non-Cell-Autonomous Function of the GPI-Anchored Protein Undicht during Septate Junction Assembly.
-
Deger et al., 2019, J. Biol. Chem. 294(48): 18092--18098
Drosophila, which lacks canonical transcription-coupled repair proteins, performs transcription-coupled repair.
-
Hudson et al., 2019, Development 146(1): dev169219
Targeted substrate degradation by Kelch controls the actin cytoskeleton during ring canal expansion.
-
Yu et al., 2019, FASEB J. 33(7): 8125--8137
Small ribonucleoprotein particle protein SmD3 governs the homeostasis of germline stem cells and the crosstalk between the spliceosome and ribosome signals in Drosophila.
-
Tettey et al., 2019, Cell Rep. 27(13): 3770--3779.e7
A Role for FACT in RNA Polymerase II Promoter-Proximal Pausing.
-
Mageeney and Ware, 2019, Mol. Biol. Cell 30(17): 2240--2253
Specialized eRpL22 paralogue-specific ribosomes regulate specific mRNA translation in spermatogenesis in Drosophila melanogaster.
-
Won et al., 2019, Cell Death Dis. 10(8): 564
ADAMTS Sol narae cleaves extracellular Wingless to generate a novel active form that regulates cell proliferation in Drosophila.
-
Elrod et al., 2019, Mol. Cell 76(5): 738--752.e7
The Integrator Complex Attenuates Promoter-Proximal Transcription at Protein-Coding Genes.
-
Luhur et al., 2019, J. Vis. Exp.: e59459
Thawing, Culturing, and Cryopreserving Drosophila Cell Lines.
-
Bertran et al., 2019, Nat. Commun. 10(1): 771
ASPP proteins discriminate between PP1 catalytic subunits through their SH3 domain and the PP1 C-tail.
-
Russo et al., 2019, Dev. Biol. 455(1): 100--111
Modulating eIF6 levels unveils the role of translation in ecdysone biosynthesis during Drosophila development.
-
Platenkamp et al., 2020, Mol. Biol. Cell 31(21): 2379--2397
The Drosophila melanogaster Rab GAP RN-tre cross-talks with the Rho1 signaling pathway to regulate nonmuscle myosin II localization and function.
-
Seong et al., 2020, Sci. Rep. 10(1): 14394
Post-transcriptional modulation of cytochrome P450s, Cyp6g1 and Cyp6g2, by miR-310s cluster is associated with DDT-resistant Drosophila melanogaster strain 91-R.
-
McGough et al., 2020, Nature 585(7823): 85--90
Glypicans shield the Wnt lipid moiety to enable signalling at a distance.
-
Kochanova et al., 2020, Nucleic Acids Res. 48(8): 4161--4178
A multi-layered structure of the interphase chromocenter revealed by proximity-based biotinylation.
-
Liu et al., 2020, Nat. Commun. 11(1): 2266
Par complex cluster formation mediated by phase separation.
-
Gozalo et al., 2020, Mol. Cell 77(1): 67--81.e7
Core Components of the Nuclear Pore Bind Distinct States of Chromatin and Contribute to Polycomb Repression.
-
Nam and Cho, 2020, BMC Dev. Biol. 20(1): 14
Wingless and Archipelago, a fly E3 ubiquitin ligase and a homolog of human tumor suppressor FBW7, show an antagonistic relationship in wing development.
-
Cunha-Silva et al., 2020, J. Cell Biol. 219(3): e201906039
Mps1-mediated release of Mad1 from nuclear pores ensures the fidelity of chromosome segregation.
-
Vaid et al., 2020, Nucleic Acids Res. 48(9): 4877--4890
Release of promoter-proximal paused Pol II in response to histone deacetylase inhibition.
-
Csordás et al., 2020, eLife 9: e57297
Eater cooperates with Multiplexin to drive the formation of hematopoietic compartments.
-
Hao et al., 2020, Genome Res. 30(11): 1570--1582
Active retrotransposons help maintain pericentromeric heterochromatin required for faithful cell division.
-
Han et al., 2020, Cell Death Dis. 11(11): 944
Exosomal arrow (Arr)/lipoprotein receptor protein 6 (LRP6) in Drosophila melanogaster increases the extracellular level of Sol narae (Sona) in a Wnt-independent manner.
-
Sethi et al., 2020, Nat. Methods 17(8): 807--814
Supervised enhancer prediction with epigenetic pattern recognition and targeted validation.
-
Garcia-Marques et al., 2020, Nat. Neurosci. 23(12): 1618--1628
A programmable sequence of reporters for lineage analysis.
-
Luo et al., 2020, eLife 9: e52416
Repression of interrupted and intact rDNA by the SUMO pathway in Drosophila melanogaster.
-
Stapornwongkul et al., 2020, Science 370(6514): 321--327
Patterning and growth control in vivo by an engineered GFP gradient.
-
Chen et al., 2020, Oxid. Med. Cell. Longev. 2020: 2846727
CG8005 Mediates Transit-Amplifying Spermatogonial Divisions via Oxidative Stress in Drosophila Testes.
-
Huang et al., 2020, Mol. Cell 80(2): 345--358.e9
Integrator Recruits Protein Phosphatase 2A to Prevent Pause Release and Facilitate Transcription Termination.
-
Sawyer et al., 2020, PLoS Genet. 16(12): e1009228
Exploiting codon usage identifies intensity-specific modifiers of Ras/MAPK signaling in vivo.
-
Kasinathan et al., 2020, eLife 9: e63368
Innovation of heterochromatin functions drives rapid evolution of essential ZAD-ZNF genes in Drosophila.
-
Wang et al., 2020, Cell Prolif 53(10): e12899
RpS13 controls the homeostasis of germline stem cell niche through Rho1-mediated signals in the Drosophila testis.
-
Casler et al., 2020, Mol. Biol. Cell 31(26): 2892--2903
ESCargo: a regulatable fluorescent secretory cargo for diverse model organisms.
-
Reddington et al., 2020, Dev. Cell 55(5): 648--664.e9
Lineage-Resolved Enhancer and Promoter Usage during a Time Course of Embryogenesis.
-
Nadeau and Teets, 2020, J. Exp. Biol. 223(2): jeb212613
Evidence for a rapid cold hardening response in cultured Drosophila S2 cells.
-
Zelhof et al., 2020, PLoS Genet. 16(6): e1008890
The brachyceran de novo gene PIP82, a phosphorylation target of aPKC, is essential for proper formation and maintenance of the rhabdomeric photoreceptor apical domain in Drosophila.
-
Chen et al., 2021, PLoS Genet. 17(2): e1009371
Homeodomain protein Six4 prevents the generation of supernumerary Drosophila type II neuroblasts and premature differentiation of intermediate neural progenitors.
-
Yang and Choi, 2021, Cell Death Differ. 28(1): 233--250
Suppression of Patronin deficiency by altered Hippo signaling in Drosophila organ development.
-
Zheng et al., 2021, Cell Death Discov. 7(1): 68
Somatic CG6015 mediates cyst stem cell maintenance and germline stem cell differentiation via EGFR signaling in Drosophila testes.
-
Deliconstantinos et al., 2021, In Vivo 35(2): 859--869
Translational Control of Serrate Expression in Drosophila Cells.
-
Liu et al., 2021, Nat. Commun. 12(1): 563
A binding protein regulates myosin-7a dimerization and actin bundle assembly.
-
Tokamov et al., 2021, eLife 10: e62326
Negative feedback couples Hippo pathway activation with Kibra degradation independent of Yorkie-mediated transcription.
-
Aleman et al., 2021, Cell Rep. 35(11): 109236
Correct dosage of X chromosome transcription is controlled by a nuclear pore component.
-
Regadas et al., 2021, Mol. Cell 81(8): 1766--1780.e10
A unique histone 3 lysine 14 chromatin signature underlies tissue-specific gene regulation.
-
Won and Cho, 2021, Cell Death Differ. 28(3): 1013--1025
Wg secreted by conventional Golgi transport diffuses and forms Wg gradient whereas Wg tethered to extracellular vesicles do not diffuse.
-
Shaheen et al., 2021, Front. Cell Dev. Biol. 9: 727972
Polycomb Requires Chaperonin Containing TCP-1 Subunit 7 for Maintaining Gene Silencing in Drosophila.
-
Kögler et al., 2021, Dev. Cell 56(16): 2348--2363.e8
Extremely rapid and reversible optogenetic perturbation of nuclear proteins in living embryos.
-
Chokshi et al., 2021, Front. Physiol. 12: 727549
NSAIDs Naproxen, Ibuprofen, Salicylate, and Aspirin Inhibit TRPM7 Channels by Cytosolic Acidification.
-
Coni et al., 2021, eLife 10: e69269
Translational control of polyamine metabolism by CNBP is required for Drosophila locomotor function.
-
Inal et al., 2021, Curr Protoc 1(7): e203
Imaging of In Vitro and In Vivo Neurons in Drosophila Using Stochastic Optical Reconstruction Microscopy.
-
Nagel et al., 2021, Biomolecules 11(11): 1672
The Membrane-Bound Notch Regulator Mnr Supports Notch Cleavage and Signaling Activity in Drosophila melanogaster.
-
Kamiyama et al., 2021, Proc. Natl. Acad. Sci. U.S.A. 118(23): e2024690118
Cell-type-specific, multicolor labeling of endogenous proteins with split fluorescent protein tags in Drosophila.
-
Mariyappa et al., 2021, G3 (Bethesda) 11(8): jkab161
Generation of Drosophila attP containing cell lines using CRISPR-Cas9.
-
Chen et al., 2021, Nat. Commun. 12(1): 6366
Temporal inhibition of chromatin looping and enhancer accessibility during neuronal remodeling.
-
Ngian et al., 2021, Aging Cell 20(5): e13348
NELF-A controls Drosophila healthspan by regulating heat-shock protein-mediated cellular protection and heterochromatin maintenance.
-
Yoshinari et al., 2021, Nat. Commun. 12(1): 4818
The sugar-responsive enteroendocrine neuropeptide F regulates lipid metabolism through glucagon-like and insulin-like hormones in Drosophila melanogaster.
-
Mok and Choi, 2021, Proc. Natl. Acad. Sci. U.S.A. 118(4): e2010140118
Novel function of N-acetyltransferase for microtubule stability and JNK signaling in Drosophila organ development.
-
Wang et al., 2021, Exp. Cell Res. 402(1): 112511
Wnt6 regulates the homeostasis of the stem cell niche via Rac1-and Cdc42-mediated noncanonical Wnt signalling pathways in Drosophila testis.
-
Cho et al., 2021, Mol. Cells 44(1): 13--25
Anastral Spindle 3/Rotatin Stabilizes Sol narae and Promotes Cell Survival in Drosophila melanogaster.
-
Rosenthal et al., 2021, Proc. Natl. Acad. Sci. U.S.A. 118(23): e2004685118
Temporal regulation of nicotinic acetylcholine receptor subunits supports central cholinergic synapse development in Drosophila.
-
Yang et al., 2021, Cell Death Dis. 12(9): 811
Topoisomerase II is regulated by translationally controlled tumor protein for cell survival during organ growth in Drosophila.
-
Yang et al., 2021, eLife 10: e65770
Competitive coordination of the dual roles of the Hedgehog co-receptor in homophilic adhesion and signal reception.
-
Patel et al., 2022, Nat. Commun. 13(1): 1185
Cytonemes coordinate asymmetric signaling and organization in the Drosophila muscle progenitor niche.
-
Nandi et al., 2022, eLife 11: e72169
A phosphoswitch at acinus-serine437 controls autophagic responses to cadmium exposure and neurodegenerative stress.
-
Nam et al., 2022, Cell Death Discov. 8(1): 146
Tctp regulates the level and localization of Foxo for cell growth in Drosophila.
-
Messina et al., 2022, BMC Biol. 20(1): 172
Evolutionary conserved relocation of chromatin remodeling complexes to the mitotic apparatus.
-
Schiemann et al., 2022, Nat. Commun. 13(1): 4420
Neprilysins regulate muscle contraction and heart function via cleavage of SERCA-inhibitory micropeptides.
-
Banzai et al., 2022, Neurosci Insights 17: 26331055211069939
A Genetic Toolkit for Simultaneous Generation of LexA- and QF-Expressing Clones in Selected Cell Types in Drosophila.
-
Gao et al., 2022, Mol. Cell 82(7): 1313--1328.e8
Lipid-mediated phase separation of AGO proteins on the ER controls nascent-peptide ubiquitination.
-
Munden et al., 2022, Sci. Rep. 12(1): 6903
Identification of replication fork-associated proteins in Drosophila embryos and cultured cells using iPOND coupled to quantitative mass spectrometry.
-
Han et al., 2022, Genetics 221(3): iyac077
Ongoing transposition in cell culture reveals the phylogeny of diverse Drosophila S2 sublines.
-
Mok and Choi, 2022, Cell Death Dis. 13(2): 101
Modulation of Hippo signaling by Mnat9 N-acetyltransferase for normal growth and tumorigenesis in Drosophila.
-
Yang et al., 2022, eLife 11: e73357
The NDNF-like factor Nord is a Hedgehog-induced extracellular BMP modulator that regulates Drosophila wing patterning and growth.
-
Kiparaki et al., 2022, eLife 11: e71705
The transcription factor Xrp1 orchestrates both reduced translation and cell competition upon defective ribosome assembly or function.
-
Ueda et al., 2022, J. Cell Sci. 135(7): jcs259092
Recruitment of Peroxin 14 to lipid droplets affects lipid storage in Drosophila.
-
McKowen et al., 2022, G3 (Bethesda) 12(11): jkac223
The Drosophila BEAF insulator protein interacts with the polybromo subunit of the PBAP chromatin remodeling complex.
-
Deger et al., 2022, Proc. Natl. Acad. Sci. U.S.A. 119(9): e2123163119
CSB-independent, XPC-dependent transcription-coupled repair in Drosophila.
-
Cairrão et al., 2022, Nat. Commun. 13(1): 1587
Pumilio protects Xbp1 mRNA from regulated Ire1-dependent decay.
-
Merrill et al., 2022, BMC Genomics 23(1): 399
Harnessing changes in open chromatin determined by ATAC-seq to generate insulin-responsive reporter constructs.
-
Deng et al., 2022, PLoS Biol. 20(10): e3001834
Parafibromin governs cell polarity and centrosome assembly in Drosophila neural stem cells.
-
Mariyappa et al., 2022, G3 (Bethesda) 12(2): jkab403
A novel transposable element-based authentication protocol for Drosophila cell lines.
-
Starke et al., 2022, PLoS Genet. 18(2): e1010084
FXS causing missense mutations disrupt FMRP granule formation, dynamics, and function.
-
Schellinger et al., 2022, Curr. Biol. 32(6): 1429--1438.e6
Chloride oscillation in pacemaker neurons regulates circadian rhythms through a chloride-sensing WNK kinase signaling cascade.
-
Du et al., 2022, Nat. Commun. 13(1): 3482
GPI-anchored FGF directs cytoneme-mediated bidirectional contacts to regulate its tissue-specific dispersion.
-
Munden et al., 2022, J. Mol. Biol. 434(13): 167645
R-loop Mapping and Characterization During Drosophila Embryogenesis Reveals Developmental Plasticity in R-loop Signatures.
-
Amankwaa et al., 2022, Life Sci Alliance 5(12): e202201536
Drosophila insulator proteins exhibit in vivo liquid-liquid phase separation properties.
-
Popova et al., 2022, Cells 11(14): 2127
Genetic Control of Kinetochore-Driven Microtubule Growth in Drosophila Mitosis.
-
Mitra et al., 2022, Biochim Biophys Acta Mol Cell Res 1869(10): 119322
Isoforms of the transcriptional cofactor SIN3 differentially regulate genes necessary for energy metabolism and cell survival.
-
Gao et al., 2022, STAR Protoc 3(3): 101596
Optimized protocols for RNA-induced silencing complex assembly and cleavage in cultured Drosophila cells.
-
Vishwakarma et al., 2022, Development 149(15): dev200519
Multifunctional role of GPCR signaling in epithelial tube formation.
-
Singh et al., 2022, J. Neurosci. 42(31): 6007--6019
Dual Leucine Zipper Kinase Regulates Dscam Expression through a Noncanonical Function of the Cytoplasmic Poly(A)-Binding Protein.
-
Grunchec et al., 2022, PLoS ONE 17(8): e0273198
Single amino-acid mutation in a Drosophila melanogaster ribosomal protein: An insight in uL11 transcriptional activity.
-
Singh and Kim, 2022, MicroPubl Biol 2022:
Generation and validation of pX-UASTattB for dose-dependent misexpression studies in Drosophila.
-
Sreejith et al., 2022, PLoS Genet. 18(9): e1010385
Imp interacts with Lin28 to regulate adult stem cell proliferation in the Drosophila intestine.
-
Hunt et al., 2022, Mol. Cell 82(19): 3580--3597.e9
p300/CBP sustains Polycomb silencing by non-enzymatic functions.
-
Liu et al., 2022, Cell Rep. 41(7): 111640
Ptp61F integrates Hippo, TOR, and actomyosin pathways to control three-dimensional organ size.
-
Gao et al., 2022, Cell Death Differ. 29(12): 2545--2561
Wun2-mediated integrin recycling promotes apoptotic cell clearance in Drosophila melanogaster.
-
Moniot-Perron et al., 2023, Cell Rep. 42(1): 111967
The Drosophila Fab-7 boundary modulates Abd-B gene activity by guiding an inversion of collinear chromatin organization and alternate promoter use.
-
Huang et al., 2023, iScience 26(4): 106490
Coordination of tissue homeostasis and growth by the Scribble-α-Catenin-Septate junction complex.
-
Wang et al., 2023, Dev. Cell 58(21): 2249--2260.e9
Mechanical stimulation from the surrounding tissue activates mitochondrial energy metabolism in Drosophila differentiating germ cells.
-
Shi et al., 2023, Development 150(24): dev201958
An EMC-Hpo-Yki axis maintains intestinal homeostasis under physiological and pathological conditions.
-
Hsiao et al., 2023, Development 150(5): dev201034
Actin-related protein 6 facilitates proneural protein-induced gene activation for rapid neural differentiation.
-
Pueyo et al., 2023, Front. Cell Dev. Biol. 11: 1117454
Purriato is a conserved small open reading frame gene that interacts with the CASA pathway to regulate muscle homeostasis and epithelial tissue growth in Drosophila.
-
Tirgar et al., 2023, PLoS Genet. 19(3): e1010682
The histone chaperone NASP maintains H3-H4 reservoirs in the early Drosophila embryo.
-
Buhr et al., 2023, Biol. Chem. 404(5): 513--520
Neprilysin 4: an essential peptidase with multifaceted physiological relevance.
-
Vishal et al., 2023, Mol. Cell. Biol. 43(6): 241--253
Phosphorylation of the Myogenic Factor Myocyte Enhancer Factor-2 Impacts Myogenesis In Vivo.
-
Ray et al., 2023, eLife 12: e87865
Sex-specific splicing occurs genome-wide during early Drosophila embryogenesis.
-
Chen et al., 2023, Sci. Rep. 13(1): 12502
Effects of N-acetylcysteine on CG8005 gene-mediated proliferation and apoptosis of Drosophila S2 embryonic cells.
-
Tang et al., 2023, Development 150(15): dev201548
Separation of transcriptional repressor and activator functions in Drosophila HDAC3.
-
Song and Ma, 2023, Cell Death Dis. 14(9): 602
E2 enzyme Bruce negatively regulates Hippo signaling through POSH-mediated expanded degradation.
-
Lovato et al., 2023, Dis. Model Mech. 16(9): dmm050059
Modeling a variant of unknown significance in the Drosophila ortholog of the human cardiogenic gene NKX2.5.
-
Galletta et al., 2023, Mol. Biol. Cell 34(9): br15
The E3 ligase Poe promotes Pericentrin degradation.
-
Wang et al., 2023, Free Radical Biol. Med. 208: 418--429
A Drosophila model of gestational antimony exposure uncovers growth and developmental disorders caused by disrupting oxidative stress homeostasis.
-
Godneeva et al., 2023, Cells 12(22): 2629
Impact of Germline Depletion of Bonus on Chromatin State in Drosophila Ovaries.
-
Godneeva et al., 2023, eLife 12: RP89493
SUMOylation of Bonus, the Drosophila homolog of Transcription Intermediary Factor 1, safeguards germline identity by recruiting repressive chromatin complexes to silence tissue-specific genes.
-
Bileckyj et al., 2023, J. Cardiovasc. Dev. Dis. 10(12): 494
Drosophila as a Model to Understand Second Heart Field Development.
-
Strutt et al., 2023, Curr. Biol. 33(24): 5340--5354.e6
Molecular symmetry breaking in the Frizzled-dependent planar polarity pathway.
-
Hunt et al., 2024, Genome Biol. 25(1): 2
Tissue-specific RNA Polymerase II promoter-proximal pause release and burst kinetics in a Drosophila embryonic patterning network.
-
Tokamov et al., 2024, Mol. Biol. Cell 35(1): ar2
Cortical tension promotes Kibra degradation via Par-1.
-
Yamamoto-Hino et al., 2024, J. Cell Biol. 223(2): e202301062
PIGB maintains nuclear lamina organization in skeletal muscle of Drosophila.
-
Lobb-Rabe et al., 2024, eNeuro 11(2): ENEURO.0184--ENEURO.23.2023
Neuronal Wiring Receptors Dprs and DIPs Are GPI Anchored and This Modification Contributes to Their Cell Surface Organization.
-
Guzman et al., 2024, Infect. Immun. 92(3): e0056022
Drosophila melanogaster Sting mediates Coxiella burnetii infection by reducing accumulation of reactive oxygen species.
-
Grmai et al., 2024, Cell Rep. 43(3): 113863
Integrated stress response signaling acts as a metabolic sensor in fat tissues to regulate oocyte maturation and ovulation.
-
Chen et al., 2024, MBio 15(4): e0137823
Regulation of phase separation and antiviral activity of Cactin by glycolytic enzyme PGK via phosphorylation in Drosophila.
-
Teng et al., 2024, Nat. Commun. 15(1): 5151
Topoisomerase I is an evolutionarily conserved key regulator for satellite DNA transcription.
-
Jayakrishnan et al., 2024, Nucleic Acids Res. 52(13): 7627--7649
Genomic context-dependent histone H3K36 methylation by three Drosophila methyltransferases and implications for dedicated chromatin readers.
-
Lin et al., 2024, Mol. Cell 84(15): 2900--2917.e10
Cytoplasmic binding partners of the Integrator endonuclease INTS11 and its paralog CPSF73 are required for their nuclear function.
-
Matakatsu and Fehon, 2024, J. Cell Biol. 223(12): e202406119
Dachsous and Fat coordinately repress the Dachs-Dlish-Approximated complex to control growth.
-
Wensveen et al., 2024, Nat. Commun. 15(1): 8984
Double-strand breaks in facultative heterochromatin require specific movements and chromatin changes for efficient repair.
-
Choudhury et al., 2024, eLife 13: e95718
The role of RNA in the maintenance of chromatin domains as revealed by antibody-mediated proximity labelling coupled to mass spectrometry.
-
Huang et al., 2024, Redox Biol. 76: 103315
Copper overload exacerbates testicular aging mediated by lncRNA:CR43306 deficiency through ferroptosis in Drosophila.
-
Kim et al., 2024, eLife 13: RP96592
Rab11 suppresses neuronal stress signaling by localizing dual leucine zipper kinase to axon terminals for protein turnover.
-
Kim et al., 2024, Mol. Biol. Cell 35(12): ar147
EB-SUN, a new microtubule plus-end tracking protein in Drosophila.
-
Zhao et al., 2024, Commun. Biol. 7(1): 1481
Neurexin facilitates glycosylation of Dystroglycan to sustain muscle architecture and function in Drosophila.
-
Tripathi and Irvine, 2024, Development 151(23): dev202919
Contributions of the Dachsous intracellular domain to Dachsous-Fat signaling.
-
Gonçalves et al., 2025, EMBO Rep. 26(2): 307--328
The Dystrophin-Dystroglycan complex ensures cytokinesis efficiency in Drosophila epithelia.
-
Hilu-Dadia et al., 2025, Cell Rep. 44(1): 115201
Santa-maria is a glial phagocytic receptor that acts with SIMU to recognize and engulf apoptotic neurons.