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Rebay et al., 1991, Cell 67: 687--699
Specific EGF repeats of Notch mediate interactions with Delta and Serrate: implications for Notch as a multifunctional receptor.
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Klueg et al., 1998, Mol. Biol. Cell 9(7): 1709--1723
Complex proteolytic processing acts on Delta, a transmembrane ligand for notch, during Drosophila development.
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Qi et al., 1999, Science 283(5398): 91--94
Processing of the Notch ligand delta by the metalloprotease Kuzbanian.
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Rand et al., 2000, Mol. Cell. Biol. 20(5): 1825--1835
Calcium depletion dissociates and activates heterodimeric Notch receptors.
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Mishra-Gorur et al., 2002, J. Cell Biol. 159(2): 313--324
Down-regulation of Delta by proteolytic processing.
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Wesley and Mok, 2003, Mol. Cell. Biol. 23(16): 5581--5593
Regulation of Notch signaling by a novel mechanism involving suppressor of hairless stability and carboxyl terminus-truncated Notch.
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Bland et al., 2003, J. Biol. Chem. 278(16): 13607--13610
Notch-induced proteolysis and nuclear localization of the Delta ligand.
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Okajima et al., 2003, J. Biol. Chem. 278(43): 42340--42345
Modulation of Notch-ligand binding by protein O-fucosyltransferase 1 and fringe.
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Lei et al., 2003, Development 130(26): 6411--6421
An O-fucose site in the ligand binding domain inhibits Notch activation.
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Delwig et al., 2006, Exp. Cell Res. 312(8): 1345--1360
Endocytosis-independent mechanisms of Delta ligand proteolysis.
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Delwig and Rand, 2008, Cell. Molec. Life Sci. 65(14): 2232--2243
Kuz and TACE can activate Notch independent of ligand.
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Lake et al., 2009, PLoS ONE 4(8): e6728
In vivo analysis of the Notch receptor S1 cleavage.
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Leonardi et al., 2011, Development 138(16): 3569--3578
Multiple O-glucosylation sites on Notch function as a buffer against temperature-dependent loss of signaling.
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Kapuria et al., 2012, PLoS Genet. 8(11): e1003045
Notch-Mediated Suppression of TSC2 Expression Regulates Cell Differentiation in the Drosophila Intestinal Stem Cell Lineage.
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Whiteman et al., 2013, J. Biol. Chem. 288(10): 7305--7312
Molecular basis for jagged-1/serrate ligand recognition by the notch receptor.
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Lee et al., 2017, PLoS Genet. 13(4): e1006723
Xylosylation of the Notch receptor preserves the balance between its activation by trans-Delta and inhibition by cis-ligands in Drosophila.