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  • Flybase
    Pubmed
    Schneider, 1972, J. Embryol. exp. Morphol. 27: 353--365
    Cell lines derived from late embryonic stages of Drosophila melanogaster.
    • Keywords:
    • establishment of cell lines
  • Flybase
    Pubmed
    DOI
    Berger et al., 1978, Dev. Biol. 62: 498--511
    Ecdysone-induced changes in morphology and protein synthesis in Drosophila cell cultures.
    • Keywords:
    • ecdysone
    • morphology
    • proteomics
  • Flybase
    Pubmed
    DOI
    Steiner et al., 1982, Infect. Immun. 35(1): 296--304
    Cultivation and partial characterization of spiroplasmas in cell cultures.
    • Keywords:
    • spiroplasma
  • Flybase
    Koval, 1983, Radiat. Res. 96: 127--134
    Radiosensitivity of cultured insect cells.
    • Keywords:
    • radiation sensitivity
  • Pubmed
    Koval, 1983, PNAS 80(15):4752-5.
    • Keywords:
    • radiation sensitivity
  • Flybase
    Pubmed
    DOI
    Tomasovic and Koval, 1985, Int. J. Radiat. Biol. Phys. Chem. Med. 48: 635--650
    Relationship between cell survival and heat-stress protein synthesis in a Drosophila cell line.
    • Keywords:
    • heat shock
  • Flybase
    Pubmed
    DOI
    Koval, 1987, Experientia 43: 445--446
    Photoreactivation of UV damage in cultured Drosophila cells.
    • Keywords:
    • DNA damage
  • Flybase
    Pubmed
    DOI
    Bashiruddin and Martin, 1987, Intervirology 28: 122--124
    Proteins induced by Boolarra virus in Drosophila melanogaster line 1 cells.
    • Keywords:
    • viruses
  • Pubmed
    Koval, 1987, In Vitro Cell Dev Biol. 23(11):733-7
    • Keywords:
    • cell death
  • Flybase
    Pubmed
    DOI
    Pimentel et al., 1996, Biochem. Biophys. Res. Commun. 226(3): 855--861
    Insulin acts as an embryonic growth factor for Drosophila neural cells.
    • Keywords:
    • insulin signalling
  • Flybase
    Echalier, 1997, Drosophila cells in culture.
    Drosophila cells in culture.
    • Keywords:
    • establishment of cell lines
  • Flybase
    Pubmed
    DOI
    Schatten et al., 1998, Cell Tissue Res. 294(3): 525--535
    The cytoskeleton of Drosophila-derived Schneider line-1 and Kc23 cells undergoes significant changes during long-term culture.
    • Keywords:
    • cytoskeleton
  • Flybase
    Cherbas and Cherbas, 1998, Roberts, 1998: 319--346
    Cell culture.
    • Keywords:
    • proteomics
  • Flybase
    Pubmed
    DOI
    Kwa et al., 1998, J. Invert. Path. 71(2): 121--127
    Toxicity and binding properties of the Bacillus thuringiensis delta-endotoxin Cry1C to cultured insect cells.
    • Keywords:
    • toxins
  • Flybase
    Pubmed
    DOI
    Anderson et al., 2002, Dev. Genes Evol. 212(3): 107--113
    A new family of cyclophilins with an RNA recognition motif that interact with members of the trx/MLL protein family in Drosophila and human cells.
    • Keywords:
    • Hox targets
  • Flybase
    Pubmed
    DOI
    Lannan et al., 2007, J. Virol. 81(17): 9319--9330
    Baculovirus caspase inhibitors P49 and P35 block virus-induced apoptosis downstream of effector caspase DrICE activation in Drosophila melanogaster cells.
    • Keywords:
    • apoptosis
    • viruses
  • Flybase
    Pubmed
    DOI
    Settles and Friesen, 2008, J. Virol. 82(3): 1378--1388
    Flock house virus induces apoptosis by depletion of Drosophila inhibitor-of-apoptosis protein DIAP1.
    • Keywords:
    • viruses
  • Flybase
    Cherbas, 2008.11.12, Cell lines from the DGRC.
    Cell lines from the DGRC.
  • Flybase
    Pubmed
    DOI
    Sabin et al., 2009, Cell 138(2): 340--351
    Ars2 regulates both miRNA- and siRNA- dependent silencing and suppresses RNA virus infection in Drosophila.
    • Keywords:
    • RNAi
    • viruses
  • Flybase
    Pubmed
    DOI
    Moser et al., 2010, PLoS Pathog. 6(6): e1000954
    A Kinome RNAi Screen Identified AMPK as Promoting Poxvirus Entry through the Control of Actin Dynamics.
    • Keywords:
    • disease models
    • RNAi
    • viruses
  • Flybase
    Pubmed
    DOI
    Cherbas et al., 2011, Genome Res. 21(2): 301--314
    The transcriptional diversity of 25 Drosophila cell lines.
    • Keywords:
    • transcriptome
  • Flybase
    Pubmed
    DOI
    Jovel and Schneemann, 2011, Virology 419(1): 43--53
    Molecular characterization of Drosophila cells persistently infected with Flock House virus.
    • Keywords:
    • viruses
  • Flybase
    Pubmed
    DOI
    Rose et al., 2011, Cell Host Microbe 10(2): 97--104
    Natural resistance-associated macrophage protein is a cellular receptor for sindbis virus in both insect and Mammalian hosts.
    • Keywords:
    • viruses
  • Flybase
    Pubmed
    DOI
    Backes et al., 2012, Cell Host Microbe 12(2): 200--210
    Degradation of host microRNAs by poxvirus poly(A) polymerase reveals terminal RNA methylation as a protective antiviral mechanism.
  • Flybase
    Pubmed
    DOI
    Mitchell and Friesen, 2012, J. Virol. 86(24): 13542--13553
    Baculoviruses modulate a proapoptotic DNA damage response to promote virus multiplication.
  • Flybase
    Pubmed
    DOI
    Lee et al., 2014, Genome Biol. 15(8): R70
    DNA copy number evolution in Drosophila cell lines.
    • Keywords:
    • copy number variation
  • Flybase
    Pubmed
    DOI
    Wen et al., 2014, Genome Res. 24(7): 1236--1250
    Diversity of miRNAs, siRNAs, and piRNAs across 25 Drosophila cell lines.
    • Keywords:
    • sRNAs
    • transcriptome
  • Flybase
    Pubmed
    DOI
    Brown et al., 2014, Nature 512(7515): 393--399
    Diversity and dynamics of the Drosophila transcriptome.
    • Keywords:
    • transcriptome
  • Flybase
    Pubmed
    DOI
    Li et al., 2014, Genome Res. 24(7): 1086--1101
    Comparison of D. melanogaster and C. elegans developmental stages, tissues, and cells by modENCODE RNA-seq data.
    • Keywords:
    • transcriptome
  • Flybase
    Pubmed
    DOI
    Westholm et al., 2014, Cell Rep. 9(5): 1966--1980
    Genome-wide Analysis of Drosophila Circular RNAs Reveals Their Structural and Sequence Properties and Age-Dependent Neural Accumulation.
    • Keywords:
    • circular RNAs
    • sRNAs
  • Flybase
    Pubmed
    DOI
    Panda et al., 2014, Proc. Natl. Acad. Sci. U.S.A. 111(37): E3890--E3899
    Nup98 promotes antiviral gene expression to restrict RNA viral infection in Drosophila.
  • Flybase
    Pubmed
    DOI
    Webster et al., 2015, PLoS Biol. 13(7): e1002210
    The Discovery, Distribution, and Evolution of Viruses Associated with Drosophila melanogaster.
    • Keywords:
    • viruses
  • Flybase
    Pubmed
    DOI
    Duff et al., 2015, Nature 521(7552): 376--379
    Genome-wide identification of zero nucleotide recursive splicing in Drosophila.
    • Keywords:
    • splicing
  • Flybase
    Pubmed
    DOI
    Rahman et al., 2015, Nucleic Acids Res. 43(22): 10655--10672
    Unique transposon landscapes are pervasive across Drosophila melanogaster genomes.
    • Keywords:
    • transposons
  • Flybase
    Pubmed
    DOI
    Kanoh et al., 2015, Sci. Signal. 8(400): ra107
    Genome-wide RNAi screening implicates the E3 ubiquitin ligase Sherpa in mediating innate immune signaling by Toll in Drosophila adults.
    • Keywords:
    • immune response
    • SUMOylation
  • Flybase
    Pubmed
    DOI
    Sansone et al., 2015, Cell Host Microbe 18(5): 571--581
    Microbiota-Dependent Priming of Antiviral Intestinal Immunity in Drosophila.
    • Keywords:
    • immune response
    • viruses
  • Flybase
    Pubmed
    DOI
    Kramer et al., 2015, Genes Dev. 29(20): 2168--2182
    Combinatorial control of Drosophila circular RNA expression by intronic repeats, hnRNPs, and SR proteins.
  • Flybase
    Pubmed
    DOI
    Stoiber et al., 2016, G3 (Bethesda) 6(3): 683--694
    Diverse Hormone Response Networks in 41 Independent Drosophila Cell Lines.
    • Keywords:
    • ecdysone
    • transcriptome
  • Flybase
    Pubmed
    DOI
    Molleston et al., 2016, Genes Dev. 30(14): 1658--1670
    A conserved virus-induced cytoplasmic TRAMP-like complex recruits the exosome to target viral RNA for degradation.
    • Keywords:
    • viruses
  • Flybase
    Pubmed
    DOI
    Zhang et al., 2016, Nature 535(7610): 164--168
    A CRISPR screen defines a signal peptide processing pathway required by flaviviruses.
    • Keywords:
    • viruses
  • Flybase
    Bairoch, 2016, The Cellosaurus: a cell line knowledge resource.
    The Cellosaurus: a cell line knowledge resource.
  • Flybase
    Pubmed
    DOI
    Liang et al., 2017, Mol. Cell 68(5): 940--954.e3
    The Output of Protein-Coding Genes Shifts to Circular RNAs When the Pre-mRNA Processing Machinery Is Limiting.
  • Flybase
    Pubmed
    DOI
    Huang et al., 2018, Genes Dev. 32(9-10): 639--644
    A length-dependent evolutionarily conserved pathway controls nuclear export of circular RNAs.
  • Flybase
    Pubmed
    DOI
    Kennerdell et al., 2018, Nat. Commun. 9(1): 4188
    MiR-34 inhibits polycomb repressive complex 2 to modulate chaperone expression and promote healthy brain aging.
  • Flybase
    Pubmed
    DOI
    Nonaka et al., 2018, Biochem. Biophys. Res. Commun. 506(3): 510--515
    Characterization of Spz5 as a novel ligand for Drosophila Toll-1 receptor.
  • Flybase
    Pubmed
    DOI
    Hodgson et al., 2019, Virology 527: 1--11
    Identification of insect genes involved in baculovirus AcMNPV entry into insect cells.
  • Flybase
    Pubmed
    DOI
    Elrod et al., 2019, Mol. Cell 76(5): 738--752.e7
    The Integrator Complex Attenuates Promoter-Proximal Transcription at Protein-Coding Genes.
  • Flybase
    Pubmed
    DOI
    Neal et al., 2019, BMC Dev. Biol. 19(1): 1
    Drosophila ML-DmD17-c3 cells respond robustly to Dpp and exhibit complex transcriptional feedback on BMP signaling components.
  • Flybase
    Pubmed
    DOI
    Tatomer et al., 2019, Genes Dev. 33(21-22): 1525--1538
    The Integrator complex cleaves nascent mRNAs to attenuate transcription.
  • Flybase
    Pubmed
    DOI
    Kanoh et al., 2019, Biochem. Biophys. Res. Commun. 508(1): 332--337
    Dual comprehensive approach to decipher the Drosophila Toll pathway, ex vivo RNAi screenings and immunoprecipitation-mass spectrometry.
  • Flybase
    Pubmed
    DOI
    Tatomer and Wilusz, 2019, Cold Spring Harbor Symp. Quant. Biol. 84: 83--93
    Attenuation of Eukaryotic Protein-Coding Gene Expression via Premature Transcription Termination.
  • Flybase
    Pubmed
    DOI
    Jia et al., 2019, Cell Discov. 5: 45
    Defining an evolutionarily conserved role of GW182 in circular RNA degradation.
  • Flybase
    Pubmed
    DOI
    Taschuk et al., 2020, MBio 11(5): e02623--e02620
    DDX56 Binds to Chikungunya Virus RNA To Control Infection.
  • Flybase
    Pubmed
    DOI
    Tsukada et al., 2020, Nat. Commun. 11(1): 1830
    Synthetic biology based construction of biological activity-related library of fungal decalin-containing diterpenoid pyrones.
  • Flybase
    Pubmed
    DOI
    Huang et al., 2020, Mol. Cell 80(2): 345--358.e9
    Integrator Recruits Protein Phosphatase 2A to Prevent Pause Release and Facilitate Transcription Termination.
  • Flybase
    Pubmed
    DOI
    Han et al., 2021, Genetics 219(2): iyab113
    Transposable element profiles reveal cell line identity and loss of heterozygosity in Drosophila cell culture.
  • Flybase
    Pubmed
    DOI
    Dib et al., 2021, Front. Genet. 12: 714152
    Pri smORF Peptides Are Wide Mediators of Ecdysone Signaling, Contributing to Shape Spatiotemporal Responses.
  • Flybase
    Pubmed
    DOI
    Kanoh et al., 2021, iScience 24(12): 103473
    cGMP signaling pathway that modulates NF-κB activation in innate immune responses.
  • Flybase
    Pubmed
    DOI
    Liang et al., 2021, Methods 196: 121--128
    Use of circular RNAs as markers of readthrough transcription to identify factors regulating cleavage/polyadenylation events.
  • Flybase
    Pubmed
    DOI
    Sheffield et al., 2021, G3 (Bethesda) 11(7): jkab116
    Age-dependent impairment of disease tolerance is associated with a robust transcriptional response following RNA virus infection in Drosophila.
  • Flybase
    Pubmed
    DOI
    Lewerentz et al., 2022, BMC Genomics 23(1): 276
    Transposon activity, local duplications and propagation of structural variants across haplotypes drive the evolution of the Drosophila S2 cell line.
  • Flybase
    Pubmed
    DOI
    Han et al., 2022, Genetics 221(3): iyac077
    Ongoing transposition in cell culture reveals the phylogeny of diverse Drosophila S2 sublines.
  • Flybase
    Pubmed
    DOI
    Hodgson et al., 2022, J. Virol. 96(12): e0021522
    Identification of Cellular Genes Involved in Baculovirus GP64 Trafficking to the Plasma Membrane.
  • Flybase
    Pubmed
    DOI
    Haugen et al., 2022, J. Biol. Chem. 298(9): 102270
    A conserved domain of Drosophila RNA-binding protein Pumilio interacts with multiple CCR4-NOT deadenylase complex subunits to repress target mRNAs.
  • Flybase
    Pubmed
    DOI
    Ai et al., 2022, Nucleic Acids Res. 50(11): e65
    CRISPR/Cas13 effectors have differing extents of off-target effects that limit their utility in eukaryotic cells.
  • Flybase
    Pubmed
    DOI
    Fujiwara et al., 2023, Mol. Cell 83(24): 4445--4460.e7
    IntS6 and the Integrator phosphatase module tune the efficiency of select premature transcription termination events.
  • Flybase
    Pubmed
    DOI
    Haugen et al., 2024, RNA 30(7): 866--890
    Regulation of the Drosophila transcriptome by Pumilio and the CCR4-NOT deadenylase complex.
  • Flybase
    Pubmed
    DOI
    Lin et al., 2024, Mol. Cell 84(15): 2900--2917.e10
    Cytoplasmic binding partners of the Integrator endonuclease INTS11 and its paralog CPSF73 are required for their nuclear function.
  • Flybase
    Pubmed
    DOI
    Connacher et al., 2024, Nucleic Acids Res. 52(20): 12669--12688
    The TRIM-NHL RNA-binding protein Brain Tumor coordinately regulates expression of the glycolytic pathway and vacuolar ATPase complex.